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ES0-002 Questions and Answers

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Asia's 2018 Heroes Of Philanthropy: placing Wealth To a very good trigger | killexams.com Real Questions and Pass4sure dumps

mannequin and actress Lin Chi-ling, who has donated greater than $1.6 million during the past three years to China's Nest-building Fund (image: VCG by way of Getty pictures)Getty

For our twelfth annual philanthropy roundup we’ve sifted via dozens of candidates to assemble a list of altruists interested in motives in the Asia-Pacific location.

The forty-member honor roll spans entrepreneurs, executives and one celeb, and in contrast to our wealth lists, these selections are subjective. The aim is to capture particular person philanthropists--these making donations with very own cash and never via their agencies (except they personal a substantial stake within the companies, in which case we trust the giving a part of their fortune). We additionally don’t encompass fundraisers or heads of nonprofits, notwithstanding they play an important function. Forbes Asia zooms in on names with the fiscal or social capital to position their stamp on concerns of magnitude.

international locations akin to China and India historically have extra names than one like Japan, the place cultural sensitivities on celebrating particular person generosity can limit our scope. As in outdated years, we goal to unearth new names, unless a past donor has made a significant pledge or contribution.

Some individuals were fervent in the arts, while many others are committed to efforts in training and healthcare throughout the place. no longer everyone is content with donating just their funds and their time; Indian tycoon Kochouseph Chittilappilly gave one in all his kidneys to a complete stranger. See our story on him right here. For the primary time, a philanthropist from Cambodia makes the checklist: Suwanna Gauntlett, an American residing there for 18 years, has dedicated herself to guarding rain forests and natural world within the nation.

more On Forbes: Asia's 2018 Heroes Of Philanthropy: Charity Is New To India's New-economic system Titans


Pamela Galli, 81

Cofounder, Galli property winery

In December, Galli donated $3.5 million to the college of Melbourne for a professorial chair in scientific biology. The giving follows similar donations in 2012 and 2013 to endow chairs in melanoma research and developmental medicine at the tuition of Melbourne and its associate institutions, as well as analysis fellowships. Galli cofounded Galli property vineyard along with her husband, Lorenzo, a property developer who died of epidermis melanoma in 2004.

Anthony Pratt (photograph: Getty photos)Getty

Anthony Pratt fifty eight

international Chairman, Pratt/Visy Industries

In August 2017 Pratt pledged to donate $seven hundred million over his lifetime to charitable reasons, including medical research and the arts. His family's Pratt basis, situated by way of his late father, Richard, and mom,Jeanne, has additionally donated greater than $one hundred seventy five million considering that 1978. He built his grandfather's container manufacturer, Visy, into one of the vital world's biggest privately owned packaging and recycling organizations.

Isaac Wakil, 91

Property Investor

along with his spouse, Susan, who died in may additionally, Wakil has donated $50 million to fitness, education, arts and Jewish explanations. He used his garment-change fortune to buy a swath of historical structures throughout Sydney and sold the mostly derelict residences in 2014 to fund his groundwork. Donations consist of $14 million in 2017 to the art Gallery of latest South Wales and $25 million in 2016 to the school of Sydney for the Susan Wakil health building, due to open next year.


Suwanna Gauntlett. Cambodia: girl Of The WildAntoine Raab for Forbes

Suwanna Gauntlett, 69

founding father of flora and fauna Alliance

one among Asia's most ardent environmental and animal-welfare advocates, Suwanna Gauntlett, has headquartered a series of conservation organizations that have devoted decades to protecting essential habitats around the world.

American-born Gauntlett, an heir to the Upjohn pharmaceutical fortune who's resided in Cambodia for 18 years, was a founding father of WildAid, which has battled the slaughter of sharks for his or her fins as well as ivory looking in Africa. She later shaped wildlife Alliance, in Cambodia, and is hailed for combating rampant land clearing and animal poaching. A former environmental advisor for multinational companies, Gauntlett estimates that she has spent $30 million to finance wildlife Alliance, which oversees conservation in Cambodia's Cardamom Mountains. "it's one of the vital important areas of biodiversity within the vicinity," she notes.

besides keeping some of Southeast Asia's final rain forests, the enviornment is home to wild elephants and the rare wooded area range. In an imaginitive strategy, flora and fauna Alliance leased over 18,000 hectares in 2009, forming a privately run flora and fauna sanctuary. There it trains and pays its personal rangers, ensuring enforcement in an area rife with poaching and land grabs. greater than one hundred rangers make over three,500 patrols each 12 months, seizing heaps of unlawful traps. It has additionally lobbied to curb or cancel dozens of concessions for mining and agro-business all the way through the Cardamom region's thousands and thousands of acres.

remaining year, flora and fauna Alliance partnered with Thai billionaire William Heinecke's Minor neighborhood and Khiri go back and forth's YAANA Ventures to open a tented camp within the sanctuary. nine at ease tents present "glamping" within the barren region with walks by means of the rangers. All proceeds go to the environmental community to finance extra conservation work.


Cai Dongqing, Cai Xiaodong & Cai Lidong, 49, 46, 44

Founder, Chairman & CEO/vp & GM/Former Vice GM, Alpha community

The brothers proficient $14 million of their fortune in November 2017 to renovate an historical industrial zone of their native land of Shantou, Guangdong, right into a citizen's park. Named after the household's animation and toy group Alpha, the park is slated to open in early 2019 with 60,000-square-meter total enviornment and a music corridor within the core.

Chen Fashu, 58

Chairman, New Huadu Industrial community/Baiyao Holdings

Head of herbal medication company Baiyao, Chen donated $seventy two million through his Fashu foundation this April to Peking tuition, the place he serves as director emeritus, to guide the construction of scientific disciplines in analysis and skill cultivation. Chen also proficient $1.5 million this July to build highways at his homeland county of Anxi in Fujian. In September 2017, he gave a $29 million endowment to Minjiang school in nearby Fuzhou, the place looking mall conglomerate New Huadu is headquartered.

chinese billionaire Chen Fashu (photograph: VCG by means of Getty images)Getty

Dang Yanbao, forty five

Founder & Chairman, Baofeng power neighborhood

With wife Bian Haiyan, his Yanbao Charity groundwork has endowed $42 million this 12 months to fund college students, chiefly these from less developed areas in Ningxia Province, where their petrochemical conglomerate is primarily based. Baofeng makes each year contributions to the foundation, which has made $238 million in donations to aid 170,000 students considering that its inception in 2011.

Ou Zongrong, 54

Founder & Chairman, Zhenro group

His family unit's utterly owned property conglomerate contributed $three million in August 2017 to construct a cultural plaza in his homeland of Putian, Fujian province, featuring a 32-meter-high statue of Mazu, a goddess commonly revered in the vicinity. ultimate yr neighborhood affiliates and Ou donated over $2 million to Zhenro basis, which has launched lengthy-term courses on account that 2013 similar to hello, Neighbour, which organizes festivals, infants's e-book golf equipment and different neighborhood activities. a different software, Holy Land, helps rural residents develop greener items and preserve local tradition. The foundation has also offered aid to survivors from mess ups such as the Sichuan earthquakes.

Campus Heroes: Yeung Kwok Keung, Yang Huiyan (left to correct).Imaginechina

Yeung Kwok Keung, Yang Huiyan, sixty four, 37

Founder & Chairman/vice chairman, nation garden

In October, through their Guoqiang Public Welfare foundation, the true property magnate and his daughter dedicated $317 million over the subsequent decade to Tsinghua school (which neither attended) to aid frontier scientific analysis and support recruit talent. It was the biggest donation ever pledged to a chinese school and the biggest made by means of the clan, too. last year they contributed $14 million for a new chemistry constructing at Tsinghua, which broke ground on the equal day as the listing pledge.

In 2014, the family unit financed the outlet of Guangdong nation garden Polytechnic, one among China's few free-of-cost junior schools, and has been making yearly contributions in the tens of millions.

Zhang Jianbin, 51

Founder & Chairman, Winfast keeping

installation Winfast Charity foundation in 2017 with $29 million from his funding firm and $117 million of his own. The groundwork has launched scholarships at eight universities in the company's base of Nanjing, Jiangsu, exceptionally for students from western China or different much less developed areas. It based healthcare aid programs at seven local hospitals to assist sufferers careworn through scientific bills.

Zhang Lei, forty five

Founder & CEO, Hillhouse Capital community

Contributed $44 million in June 2017 to his alma mater Renmin institution of China to guide interdisciplinary research and boost the tuition's international have an impact on. additionally donated $15 million later that 12 months to fund the building of Westlake college, a private university that opened in April in Hangzhou, backed with the aid of China's widespread entrepreneurs including cyber web gigantic Tencent's Ma Huateng and actual property heavyweight Wanda's Wang Jianlin. Zhang sits on the board of both universities. In 2010, Zhang, who sits on Yale's board, donated $8.88 million to Yale's college of administration, the place he earned his grasp's degree. It become the greatest donation the college had ever acquired at the time.


James Chen, 57

Chairman, Wahum community Holdings

In March, the Hong Kong resident pledged $10 million to U.k.'s vision Catalyst Fund, led by means of the Queen Elizabeth Diamond Jubilee believe. A cofounder of Adlens, an eyewear outfit widely used for its adjustable-focus lenses, he says the enterprise inspired his philanthropy. He founded vision for a Nation, a charity that gives reasonably-priced glasses and first eye look after individuals in rising nations.

Mapping China: Hui Wing-MauSimon tune/SCMP

Hui Wing-Mau, 68

Founder & Chairman, Shimao community

ultimate November Hui donated the "Silk street panorama Map" to Beijing's Palace Museum. Created over four centuries in the past, the now shorter map (30-by-0.6 meters) points scenery alongside the Silk street from northwest China's Gansu Province to Mecca. It covers more than 200 locations, equivalent to Samarkand in Uzbekistan and Damascus in Syria, showcasing China's exchange and cultural exchanges all through the Ming Dynasty.

The map become bought by Hui's Hong Kong property conglomerate Shimao community at $19 million from a private collector who retrieved it after a long time of exhibition in a japanese museum. Hui realized the Palace Museum changed into seeking to add the map to its assortment and provided to help--his group, of which he is the bulk owner, additionally contributed $12 million in 2016 to the research-based renovation of 1 of the museum's halls. Hui's other philanthropic work spans opening colleges in his native land Quanzhou, Fujian, to constructing hospitals in China's poverty-troubled areas to cofounding the China red Ribbon groundwork for AIDS handle and prevention. The groundwork, where he serves as executive director, has offered reduction to 2,540 orphans in addition to opened 290 village-degree clinics in faraway and destitute areas for the reason that it changed into install in 2005.


Kochouseph Chittilappilly, sixty seven

Chairman and Chief government Officer of V-guard Industries Ltd

As his sixtieth birthday drew close, Kochouseph Chittilappilly could not assist however renowned that existence changed into respectable as he had constructed from scratch an empire comprising electrical and electronic equipment and amusement parks. nonetheless, Chittilappilly become overcome by means of the urge "to do something better with my existence." In 2011, two months after he became 60, the rich person agreed to donate the organ to an ill trucker, who changed into an entire stranger.

(See story Asia's 2018 Heroes Of Philanthropy: The tycoon Who gifted His Kidney To retailer A Stranger's existence)

Puneet Dalmia, 46

Managing Director, Dalmia Bharat

Cement czar Puneet Dalmia and his household set up the Avanee basis (named after his daughter) this 12 months with almost $three million. here is aimed at training for children from grades 3 to eight--advertising values like kindness, compassion and admire for elders. The basis rolled out a "happiness" curriculum in July incorporating these values and has informed 22,000 lecturers so far. it's now attaining a million college youngsters. Puneet is also engaged on content relating to ancient Indian philosophy, which will also be utilized to administration practising.

Anand Deshpande, 56

Chairman & Managing Director, Persistent programs

software maven who runs the $471 million (fiscal 2018 revenues) Persistent programs is on a mission to convert job seekers into job creators. He does that through his deAsra basis, which has $3 million. The Pune outfit has assisted well-nigh 9,000 small organizations. Deshpande helps entrepreneurs delivery, control and develop their agencies by offering a number of assist functions. His aim is to aid 25,000 enterprises by the 12 months 2020.

Kishore Lulla, fifty seven

govt chairman & CEO, Eros group

Earmarked $20 million for reasons based on females and youngsters. Lulla's $261 million (fiscal 2018 revenues) movie company acquires, co-produces and distributes Indian movies across the globe. through his Eros basis, he can be specializing in training of girls, above all within the western Indian states of Maharashtra and Gujarat. He also money two or three scholarships a yr for women on the UCLA film college and supports a Mumbai organization called Arpan, which works to prevent baby intercourse abuse.

Sunil Mittal, 60

Chairman, Bharti agencies

Telecom multi-millionaire and his brothers, Rakesh and Rajan, pledged to donate 10% of their wealth, including a 3% stake in listed telecom flagship Bharti Airtel, (currently valued at $500 million), to their Bharti groundwork. The dollars will partly be used to deploy the Satya Bharti school, which is due to open in 2021 and will offer free tuition to the underprivileged. Their foundation has thus far offered free schooling to greater than 45,000 babies.

Infosys Chairman Nandan Nilekani (photograph: associated Press)

Nandan & Rohini Nilekani, 63, fifty nine

Cofounder, Infosys; founder, Arghyam

Pledged to donate 50% of their wealth in November 2017 under the Giving Pledge and stated, "Wealth comes with massive responsibility and is most suitable deployed for the greater public interest." past contributions include $5 million to the premier Indian Institute of technology Bombay in Mumbai, Nandan's alma mater, and a $21.4 million endowment to Arghyam, a foundation deploy by using Rohini, which addresses water and sanitation considerations. both have additionally install the EkStep basis, an open-studying platform that has pooled resources to enhance literacy and numeracy.

Abhishek Poddar, 50

Managing director, Matheson Bosanquet

with his household, donated $7 million and 7,000 pieces from their very own collection to the Museum of art & images in Bangalore. as the first major private art museum in India's tech metropolis, set to open in 2020, it is going to have more than 15,000 works masking the gamut from contemporary and contemporary Indian paintings to images and usual tradition. Poddar, who hails from a family with hobbies in tea plantations and industrial explosives, grew to become attracted to art in excessive school and is the museum's founder and chief client. After an initial plan to accomplice with the state executive got delayed, the Poddars went ahead on their own, raising dollars by promoting 41 prized works from their assortment through a Christie's public sale.


Eddy Sariaatmadja, sixty five

Cofounder, Elang Mahkota Teknologi (Emtek)

In December, donated a scientific scanner costing more than $820,000 to the government-owned Royal Perth sanatorium (RPH) in Australia. The O-Arm Scanner permits surgeons to scan patients throughout surgical procedure and gives special 360-diploma photos. He and his wife made the contribution as each were encouraged by using their own adventure on the hospital. A graduate of the tuition of new South Wales, Sydney, he has made donations for liver transplant patients in Indonesia and pediatricians from the U. of Indonesia obtaining their doctoral levels. He changed into a benefactor of state-owned eye clinic RSCM Kirana; RSCM and his Alfa Omega basis give free cataract surgical procedures for a hundred sufferers per 30 days.


Kazuo Inamori, 86

Founder, Kyocera & KDDI

In April, his Inamori basis doubled its Kyoto Prize to $930,000, a good way to go to each and every of the three laureates for achievements in superior know-how, fundamental science, and philosophy and arts. On par with the Nobel Prize, it's viewed because the country's most prestigious award and one which covers some classes no longer traditionally represented within the Nobel. In November, he donated $seventy one million in Kyocera shares to his alma mater Kagoshima university.


G. Gnanalingam, 74

Chairman & Cofounder, Westports Holdings

deploy the Indus education basis in 2014 with $6 million pledged over 5 years to guide greater education of underprivileged Malaysian Indian college students. The basis, a partnership with the Malaysian executive and Gnanalingam and other benefactors, offers support in the variety of loans, fellowships, scholarships and awards, constantly protecting all or a part of training. given that its inception, IEF has offered "hobby-free" monetary guide worth $three million to 496 students from middle- and low-revenue families. Gnanalingam also donated $2 million to The group Chest, a charity basis set up by means of Malaysian tycoons in 2011 to donate as a minimum $24 million yearly to chinese language, Tamil and missionary colleges.

Dr. Francis Yeoh (photograph: Getty)Getty

Francis Yeoh, sixty four

govt Chairman, YTL Corp.

He and the Yeoh household donated $2.4 million to 103 charity and schooling agencies in December in honor of his billionaire father, Yeoh Tiong Lay, who died last October. A lover of the arts, the younger Yeoh become awarded the Capri Legend Humanitarian Award through the Capri Hollywood international film competition in 2016 for his philanthropy; one in every of his presents became a $1.1 million donation to a struggling Rome opera condo, Teatro dell'Opera di Roma, in 2015. The late YTL founder become usual for his charitable giving, donating $four.5 million to the Kuala Lumpur Performing Arts Centre given that it opened in 2005 and awarding $2 million to infrequent, a U.S. corporation dedicated to sustainable fisheries, including to websites in Indonesia, the Philippines and Brazil, in 2010. huge on training, the family's YTL basis has funded $25 million in scholarships to lots of of students in Malaysia.


Jose Mari "Butch" T. Albert, 68

Chairman, Fila Isport life

Gave more than $110,000 to his Operation Compassion's iRebuild in 2014, which provides emergency reduction but also works to rebuild the community with a long-term view, offering livelihood working towards and trauma counseling in the nation. yet another $sixty six,000 supported the nonprofits' iFoster, created to aid discover foster buildings for abandoned children. Albert says foster folks "just deserve to have an open coronary heart and let little ones think they are loved." one other $450,000 was given to a church in a low-salary enviornment that offers mass clinical care and food to malnourished babies.

Alice Galang Eduardo, fifty three

President & CEO, Santa Elena construction & construction Corp.

After visiting an employee's ill child at a public clinic, Eduardo determined that charity could not wait. In 2014, she donated $277,000 to construct a 320-square-meter isolation ward on the Philippines' largest executive hospital, geared toward cutting back childhood cancer mortality ranges. In 2018, she provided $370,000 to build a close-by dormitory to residence sufferers' households. a further $370,000 helped preliminary funding for Tuloy groundwork, a nonprofit in the Philippines, which cares for and educates abandoned babies. She additionally contributed $185,000 to building one hundred buildings for storm Yolanda victims and offered $184,000 to Habitat for Humanity.

Susana Abad Santos Madrigal, 63

President, Consuelo Chito Madrigal neighborhood of businesses

Granddaughter of former wealthy person-senator Vicente Madrigal has given $1 million to projects tied to her very own existence. After a daughter partly misplaced hearing in a single ear, Madrigal donated $ninety three,000 to the Catholic Ministry for the Deaf. Her eldest daughter's social motion triggered a $185,000 gift to aid early education of underprivileged toddlers; the equal volume changed into given to a church in honor of her late aunt and philanthropist Chito Madrigal. She supported a company & Accountancy building for an underresourced state university in honor of her late father, Antonio P. Madrigal, who ran a part of the clan's conglomerate. Madrigal's current focus stems from surviving breast cancer: In 2014 she initiated a $18,600-a-yr pledge to the cancer Samurai scholar Fund, to cowl scientific charges of a needy affected person. Madrigal says, "My goal is to keep a life. If i'm capable of try this, then i am happy."


Edwin Koo/Getty images for united states04a7d3d609129a9296bf7ac0608c2097) Trina Liang & Edmund Lin, forty seven, 49

MD, Templebridge Investments; associate & Director, Bain & business, Singapore

To mark their twentieth wedding anniversary, the powerhouse couple deploy the Lin groundwork Asia in 2016. they have got considering donated about $350,000 toward a variety of motives, including schooling for women and children, gender equality, animal welfare and the arts. The pair have been each lively volunteers going back to their college days at elder homes and youngsters's charities. Trina is a board member of the Singapore Committee for UN girls, promoting empowerment.

Tan Chin Hwee, forty seven

CEO, Trafigura neighborhood (Asia-Pacific)

Donated greater than $3 million in the past ten years to initiatives assisting newborns, babies and the elderly. After gazing his first daughter, who turned into born at 27 weeks, battle to continue to exist (which she did), Hwee, with the KK girls's and youngsters's health facility, set up the Premmies Endowment Fund to relieve the financial burden of 30 families every 12 months. He has additionally partnered with the Nanyang Technological institution, his alma mater, to create a application where all 33,000 students and group of workers volunteer for social factors every 12 months.

Teng Ngiek Lian, 68

CEO, target Asset management

The yr he turned 60, the veteran fund manager all started The Silent basis with $36 million to assist the unvoiced in society. The self-made investor, whose father turned into a shoemaker, has stated Warren Buffett as a major influence in each his work and philanthropy efforts. Teng focuses on environmental and social explanations, similar to assisting flora and fauna conservation via World flora and fauna Fund's Eco-clubs application in western Mongolia and helping migrant laborers in Singapore. A former managing director at Morgan Grenfell funding administration Asia and Managing Director of u.s.a.Asset administration in Singapore, Teng begun target Asset management in 1996.

Woon Tek Seng, Woon Wee Phong, Woon Wee Hao, Woon Wee Teng

70, 65, 64, 61

house owners, Killiney Kopitiam

4 siblings who personal Singapore's oldest coffee and tea shop chain, Killiney, installation the Woon Gallery of Asian artwork at Northumbria institution in the U.okay. with an preliminary reward of rare artifacts price $5 million. The gallery, which opened in July, features items from the brothers' immense collection, including antiquities relationship back to China's Han Dynasty and the Nanzhao and Dali kingdoms. The brothers, who are religious Buddhists and had been inspired to bring together art through their father, have, among plenty else, additionally funded the creation and consecration of a number of Buddha statues for temples in Thailand and Myanmar.


Hong Jong-Ryul, 99

Honorary Chairman & Founder, Kiswire

In June 2017 donated very nearly $1 million to Masan Yongma high college, west of Busan, which he attended. He had previously developed a library named Hongduk, named after a subsidiary business, for the college as smartly. Kiswire, which manufactures uniqueness steel wire items for automotive, bridge, power, construction and electronics become founded via Hong in Busan 73 years in the past. it is time-honored for its worker retention; in a single of its factories, the average age of a worker is sixty six; many have worked for the business for more than 30 years.

Kim Bong-Jin, 42

CEO & Founder, Woowa Brothers

In October 2017, Kim, who runs the No. 1 food beginning app in Korea, pledged to donate pretty much $9 million in scholarships for students from low-salary households. 1 / 4 of that will be disbursed over 5 years via a social welfare foundation dubbed The Fruit of affection. instead of building his own basis he determined to contribute via a national charity to in the reduction of operating expenses and boost effectivity.

Kim Byung-Yeol, eighty three

company proprietor

remaining September Kim donated his forests and constructions--a complete of 108,386 square meters --to the metropolis of Cheonan, where he made his money operating eating places and supermarkets. His land and buildings might be used to satisfy Cheonan's administrative needs.


Chiling Lin, forty three


Has donated greater than $1.6 million in the past three years to China's Nest-building Fund, which is used to build dormitories for schoolchildren in poverty- remote areas throughout China. via her groundwork, dependent in 2011, the model-turned-actress has raised an additional complete of $1.6 million for agencies of financially deprived babies or emergency aid initiatives in Taiwan by using launching revenue of her charity calendar every year or auctioning off her used cloth cabinet.

Asus CEO Jerry Shen (image: Hindustan instances by means of Getty pictures)Getty

Jerry Shen, fifty eight

CEO, Asustek laptop

In March, Shen deploy a $1 million have faith fund below the identify of his mother, Shen Huang Hsueh-Er, for his alma mater elementary college in Tainan in southern Taiwan. so far, about one third of the capital has been injected. The donation has considering that been used to fund extracurricular courses or summer time and iciness camps in science, math, studying and English learning for college kids of financially deprived households, who the college says account for half of its student population. A neighboring core faculty has additionally benefited from such courses. previous to that, Shen had financed equivalent courses on the grounds that 2014. Celebrating the basic school's a centesimal birthday in 2015, he contributed 30 tablet computers and 20 routers for the college's use.

Ming-Kai Tsai, sixty eight

Chairman & CEO, MediaTek

ultimate September, Tsai finalized a donation of $1.6 million to the city government in Hsinchu, where his smartphone chipmaker MediaTek is primarily based. The funds has been used to partially fund the city’s $3.eight million mission of renovating Taiwan Pavilion EXPO – the island’s sky lantern-fashioned setting up first on screen at Expo 2010 in Shanghai and later in 2013 reopened in Hsinchu. Upon the renovation's completion in 2020, the city of Hsinchu plans to turn it into a infants's castle, where younger minds can gain knowledge of to discover science. in advance of that, Tsai had given away some $640,000 for post-Morakot typhoon relief in 2009. And in 2001, he and MediaTek donated a complete of $three.2 million to fund the creation of a instant analysis lab at national Taiwan tuition.


Petch Osathanugrah, sixty four

CEO, Osotspa

Says he's earmarked $20 million to $30 million on bankrolling a latest artwork museum, more straightforward to manipulate following the lengthy-awaited IPO in October that valued his family unit holdings in its 127-yr-old beverage business at over $1 billion. After shelving two previous museum designs, Petch noted his Dib Bangkok (Dib potential "uncooked") will smash ground in March, opening in 2020. The three-story museum will demonstrate works from his massive 500-piece assortment, and revolving displays. "My ardour has all the time been for art," says the avid three-decade collector. "I just want to share this."

Malee Tangsin, 90

Chairwoman, Ramada Plaza

Bangkok Menam Riverside resort

On a discuss with to a temple in vital Thailand within the early 1980s, China-born Malee Tangsin and her late husband, Archin, have been requested via the abbot if they could help several bad boys. The boys have been dwelling on the temple while attending junior high school, however had no ability to continue on to senior high faculty. Having lately welcomed their 36th "category" of tenth graders, in complete, Malee and the family groundwork have spent about $2 million in guide of 450 boys while they attended high school in Bangkok. The boys live in a household-owned constructing at once throughout the highway from the Menam Riverside resort and take nutrition in a resort workforce canteen. Malee's seven little ones help out with supervision and container trips. while the customary students have been ethnic Thai, nowadays nearly all come from Hmong and Akha hill tribe villages in the some distance north of Thailand. After high college graduation, most go on to university or technical school.


Dominic Scriven, 55

executive Chairman, Dragon Capital

Spent pretty much $three.5 million on flora and fauna at risk, a nongovernment organization he centered in 2003, which educates local communities in Vietnam on doing away with illegal trade of natural world and conserving herbal supplies. struggle says it has helped unlock 6,500 animals returned to nature. Born in the U.ok., he has lived within the nation for 2 decades and is fluent in Vietnamese. His Dragon Capital is one of the oldest capital management organizations in Vietnam, currently managing funds with greater than $three billion in internet asset cost.

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Shu-Ching Jean Chen, Susan Cunningham, Ron Gluckman, Gloria Haraito, Jane Ho, Joyce Huang, Naazneen Karmali, Kim Hee-joung, Sunshine Lichauco de Leon, Anis Shakirah Mohd Muslimin, Lan Anh Nguyen, Anu Raghunathan, Lucinda Schmidt, James Simms and Jessica Tan.

americans generally prefer govt funding for clinical and science analysis | killexams.com Real Questions and Pass4sure dumps

Biologist Benjamin Jin conducts immunotherapy research for combating HPV+ cancers in a lab at the national Institutes of fitness country wide melanoma Institute in Bethesda, Maryland, on Feb. 7, as a part of government-funded experimental trials. (Saul Loeb/AFP/Getty images)

americans are strongly supportive of the govt investing in analysis in medication and science, in keeping with a brand new Pew analysis middle survey.

Most Americans say government investments in medical and science research usually pay offround eight-in-ten U.S. adults say government investments in scientific research (eighty%), engineering and expertise (eighty%) or simple scientific analysis (77%) always repay ultimately. only about two-in-ten trust executive funding in each and every of these areas isn't value it (19% for clinical research, 19% for engineering and know-how and 22% for simple scientific analysis).

Pew analysis center surveys in 2014 and 2009 also discovered large public assist for government investments in basic scientific analysis and engineering and expertise, even though these surveys used distinctive polling strategies and just a little diverse query wording. (Views on funding for medical analysis were not included in the past surveys.)

Majorities of political groups support basic scientific research funding, especially liberal DemocratsMajorities throughout the political spectrum agree that government investments in scientific analysis, engineering and expertise or basic scientific research pay off ultimately, however there are political ameliorations on these questions. as an instance, 92% of liberal Democrats say govt investments in basic scientific research in the end pay off. by using evaluation, sixty one% of conservative Republicans say government investments in simple analysis repay, while a sizable minority (38%) says government investments in primary scientific research “aren’t worth it.”

A 2017 Pew analysis core survey discovered a large and growing to be political divide over expanding federal spending on scientific analysis. Democrats and Democratic-leaning independents had been 27 percent points more likely than Republicans and Republican leaners to claim they would boost spending on scientific analysis. In 2001, by contrast, there become no large divide between Republicans and Democrats over expanding federal spending for scientific analysis.

the new survey additionally asked americans to weigh the value of govt versus deepest funding in research funding. A majority of americans (57%) say govt funding is basic for scientific growth, whereas 42% say private funding will ensure satisfactory progress even without govt funding. the share asserting executive investment is primary is widely according to old Pew analysis center surveys that once more used distinct survey strategies and somewhat distinctive question wording.

Two-thirds of conservative Republicans say private investment will ensure enough scientific progressLiberal Democrats and conservative Republicans have distinct views on this question. About eight-in-ten liberal Democrats (seventy eight%) say executive funding of analysis is basic for scientific growth. in contrast, 31% of conservative Republicans say government funding is fundamental, whereas two-thirds (sixty seven%) say private investment will make certain sufficient development is made, even devoid of govt funding.

notice: See topline effects and methodology here. 

issues: Federal executive, Science and Innovation

What Vets think of ‘23andMe for canine’ | killexams.com Real Questions and Pass4sure dumps

for their half, the leading dog-DNA agencies know a total lack of law is bad for their business’s recognition. “The trade can be tainted by using a nasty actor or two. We do suppose adore it’s crucial to are trying to self-adjust as most efficient we are able to,” says Hughes, of knowledge fitness. It’s why knowledge health and several other checking out organizations are collaborators in the Harmonization of Genetic trying out for canine venture.

At its core, the harmonization mission is a database of dog genes which have been linked to distinctive ailments in diverse breeds. This isn’t as fundamental because it sounds. Gene names aren’t always standardized; neither are breed names between countries. “We must make sure we’re even speakme about the equal dogs,” Llewellyn-Zaidi says, which illustrates the problem for vets delving into the genetics literature.

Getting breeds appropriate is vital as a result of many markers linked to a dog ailment are breed certain. (Some corporations offer breed-particular DNA checks to account for this.) in many circumstances, those ailment markers will on no account be found in one more breed. but in just a few infrequent instances, they can mean different things for diverse breeds. for instance, says Ekenstedt, ingredient VII deficiency is associated with light bleeding in beagles, wherein it become first found out, but with severe bleeding in Alaskan Klee Kais.

a customary vet isn’t more likely to be everyday with the details of hundreds of mutations. And really, Ekenstedt admitted that even she, a educated canine geneticist, isn’t. when I requested about a specific trait known as alanine-aminotransferase undertaking, every so often established for in dog DNA, she noted she wasn’t so established with it. “Even an expert like me can’t keep up,” she says. “No regular veterinarian has time to sustain with it. finally, I suppose we deserve to have greater experts who're extra seen for regular vets to attain out to.”

In some circumstances, the DNA-examine organizations have stepped in to fill that void. Hughes advised me her group always fields questions from consumers about their dog’s selected consequences. Embark additionally has a veterinary crew that proactively reaches out to shoppers about their results. “We don’t need somebody opening an e mail and being hit by something and never figuring out a way to interpret it,” says Adam Boyko, one in all Embark’s founders.

One Embark consumer, Emily Rose Cunningham, told me that the business reached out about her dog Dora, an American hairless terrier that had a marker linked to enlarged hearts in yet another breed. Cunningham took Dora to see a dog cardiologist. Her exam got here again normal, and Cunningham said the results returned to Embark. on the grounds that then, at least one different American hairless terrier has been found with the marker. Cunningham informed me she preferred that Embark became collecting facts for extra analysis. “i like that there’s persisted research instead of just getting verify outcomes and it’s executed,” she mentioned.

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Exploring the Science, and the Snake Oil, Behind Regenerative Stem Cell Therapy | killexams.com real questions and Pass4sure dumps

A dozen seniors ambled in to the Maple Room of the Holiday Inn in South Burlington, several of them supported by canes, walkers, scooters or spouses. A slide projected on a screen at the front of the room read, "Stop hurting and start living!"

The attendees at the free seminar, held on a Friday afternoon in early September, likely learned about it from one of several full-page advertisements in Vermont newspapers. Similar events have been held in Bennington, Montpelier, Shelburne and St. Albans City in recent months.

This particular seminar was advertised for patients suffering from chronic obstructive pulmonary disease, or COPD, an inflammatory lung condition that causes wheezing, coughing and difficulty breathing. Other ads targeted those with arthritis, diabetes, neuropathy, and chronic neck and back pain.

Though the ads differed slightly, all featured smiling seniors — holding hands, blowing soap bubbles, rising from wheelchairs — as well as glowing testimonials from anonymous patients and the tagline, "Experience healing with regenerative stem cell therapy at Stem Cell Centers!" At the bottom, in fine print, was a caveat: "Stem cell therapy is still considered experimental by the FDA," referring to the U.S. Food & Drug Administration.

As attendees took their seats, Jason Wolther, a speaker from Stem Cell Centers' corporate headquarters in Post Falls, Idaho, began his presentation. He had traveled to Vermont to recruit patients for Stem Cell Centers of Williston, a new clinic that registered with the Vermont Secretary of State's Office in April. According to Wolther, Stem Cell Centers is one of the nation's oldest and largest chains of such clinics. Its website lists 16 locations in 10 states.

Though this seminar was ostensibly for COPD patients, Wolther's 90-minute presentation covered a range of other ailments that, he suggested, could also benefit from stem cell treatments. These included arthritis, numbness in the arms and legs, spinal stenosis, osteoporosis, emphysema, and even Alzheimer's disease — all conditions that commonly afflict seniors. If attendees liked what they heard, Wolther could immediately schedule them for a consultation with the clinic's local practitioner, naturopathic physician Esti Bakty-Johnson.

"Who's got back pain? Or maybe the better question is, who doesn't have back pain? How about joint problems, knees, hips and shoulders?" Wolther asked, as a flurry of hands went up. "Well, you guys are in the right place. Those are the things we've been treating, with high degrees of success."

"This isn't covered by insurance, right?" asked a redheaded woman at the front of the room. Wolther confirmed that private insurance, Medicare and Medicaid won't pay for this therapy, which starts at about $4,500 for a single knee or hip treatment and can run as high as $15,000 for multiple treatments for conditions such as COPD and autoimmune diseases.

"Now, the FDA, in all of their great wisdom, is still classifying stem cell therapy as quote-unquote 'experimental,'" Wolther said. "After decades and decades of doing stem cell therapy, in this country and worldwide, why do you think the FDA would still be classifying these treatments as quote-unquote 'experimental'?"

"Money?" suggested one man in the room.

Stem cell therapy, Wolther continued, "is a real game changer. But we're getting a lot of pushback. Do you think big pharmaceutical companies want to see this treatment become mainstream? No! Do big pharmaceutical companies want to see you getting healthy? No! It's being driven by profits instead of by results. And who suffers because of it? Everybody in this room." Several attendees nodded in agreement.

A stem cell boom

The field of stem cell therapy, which involves repairing, engineering or replacing human tissues damaged by injury or disease, has shown enormous promise in the last decade. Researchers have made great strides in treating diseases such as leukemia and lymphoma using cells drawn from a patient's own blood, fat or bone marrow, as well as from amniotic fluid and umbilical cords.

But within the medical marketplace, promises of treatments and cures for a plethora of other diseases and conditions have gotten ahead of the science, with advertisements offering consumers stem cell therapies to treat everything from erectile dysfunction to hair loss. Until recently, much of the for-profit stem-cell industry was the Wild West, where consumers were left to figure out what was real and what wasn't — at times with disastrous consequences.

Direct-to-patient marketing events such as the recent Stem Cell Centers seminar — which sounded, at times, more like a sales pitch for a Caribbean time-share than a health care discussion — are recent phenomena in Vermont. Elsewhere, however, stem cell therapy is huge, with the number of clinics multiplying nationwide from just two in 2009 to more than 570 in 2016, according to a 2016 study published in the peer-reviewed journal Cell Stem Cell. Last year, the market research firm Mordor Intelligence valued the North American stem cell industry at $5.6 billion and predicted it will grow by nearly 16 percent by 2021.

Many clinics have opened in states with large populations of retirees, including California, Florida, Arizona and Texas. Their arrival in Vermont is understandable, given that one in five Vermonters is over the age of 60. For older Americans, especially those who've exhausted all other treatment options or simply want to avoid surgery, stem cell therapy offers a glimmer of hope.

"As we get older, we have more chronic conditions and more medical conditions," explained Dr. Michael LaMantia, head of geriatric medicine at the University of Vermont Medical Center. "Unfortunately, we still have many more advances to make in medical care for older adults, and sometimes patients can feel like the medical system isn't providing them with all the answers they're looking for."

Stem Cell Centers didn't respond to emails or phone calls requesting an interview with its local provider or with any of its Vermont patients.

Vermont has a second stem cell clinic, Vermont Regenerative Medicine in Winooski. It, too, markets its patented Regenexx stem cell orthopedic procedures directly to patients through free informational seminars. Because the FDA doesn't allow some Regenexx procedures to be performed in the U.S., Vermont Regenerative Medicine encourages patients to travel to the Cayman Islands to have them done.

The Vermont Medical Society, AARP Vermont and the UVM Center on Aging were either unaware of, or wouldn't comment on, these local stem cell clinics. LaMantia, who only learned about them shortly before being interviewed, also declined to comment on them.

He recommended that potential patients consult with a health care provider they trust before seeking any treatment. Based on information he's read from the FDA, LaMantia said, "The evidence for many stem cell therapies is just not there yet."

What Is Stem Cell Therapy?

Simply put, stem cells are the basic building blocks of all human tissue, able to divide and multiply almost without limit. According to the National Institutes of Health, adult or somatic stem cells are undifferentiated, meaning that they haven't turned into specialized cells such as blood, muscle or brain cells. That means the body won't reject them, even if they come from another person. (Stem Cell Centers uses cells obtained from donated umbilical cords.)

Researchers have known for years that stem cells play a critical role in repairing and maintaining tissues and organs throughout the body, which is why they're sometimes touted as "cure-all" or "miracle" cells. Bone marrow contains two types: hematopoietic cells, which can generate blood cells, and stromal cells, which can produce bone, cartilage and fat. Adult stem cells are different from the embryonic stem cells found early in the development of a fetus. Concerns that aborted fetuses might be used to harvest stem cells led to the 2001 federal ban on embryonic stem cell research.

According to a 2017 patient guide from the Journal of the American Medical Association, the number of clinically proven stem cell treatments remains limited. Notably, hematopoietic stem cells are routinely used for bone marrow transplants in patients with cancer and other blood or immune disorders.

Until last year, the FDA and the Federal Trade Commission largely avoided policing adult stem cell clinics. Because stem cells can be extracted from and reinjected into a patient's own body, the FDA doesn't consider them a drug. Federal rules stipulate that the cells must be human, "minimally manipulated" and used for "homologous use," or as they normally function in nature.

Medical organizations such as the American Academy of Orthopaedic Surgeons, as well as research organizations including the International Society for Cell & Gene Therapy, have grown increasingly concerned about the proliferation of stem cell clinics that offer unproven, expensive and potentially dangerous treatments.

In 2017, the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine called these clinics "an emerging public health problem" and warned consumers, "As of now, there are no proven stem cell treatments for any lung disease."

No cases of adverse medical outcomes from stem cell treatments have been reported in Vermont, according to the state Department of Health. In fact, the Vermont Board of Medical Practice declined to comment for this story, as did Vermont Health Commissioner Dr. Mark Levine. Health department spokesperson Sharon Muellers noted, "This is not currently a public health priority."

But as Americans read news stories about professional athletes — including golfer Tiger Woods, basketball superstar Kobe Bryant and tennis legend Rafael Nadal — who've experienced seemingly miraculous recoveries from injuries after receiving stem cell treatments, they have flocked to clinics in the U.S. and abroad.

Such treatments aren't without risk. As the Washington Post reported in an April 29 story, "Miracle Cure or Modern Quackery," a 69-year-old woman died in 2010 after a Florida doctor injected bone-marrow-derived stem cells into the arteries in her brain. The New York Times reported in 2016 that a man spent $300,000 on overseas "stem cell tourism," which left him with a huge tumor on his spine. And, in a widely publicized case two years ago, a Georgia woman became blind after she had stem cells injected into both eyes to treat her macular degeneration.

Making Breathing Easier

Some local physicians and researchers who are trying to develop innovative therapies are troubled by the arrival of stem cell clinics in Vermont. In addition to the potential for physical and financial harm to patients, they also fear that negative publicity about stem cell therapies threatens to cast them all in an unflattering light.

In a third-floor laboratory of UVM's Given Medical Building, Dr. Daniel Weiss is growing lungs — three disembodied mouse lungs, to be exact. Each one "breathes" ambient air with the help of a ventilator inside a Plexiglas growth chamber.

In an adjacent room is a pearly white chunk of human lung that's been "de-cellularized," or stripped of all its donor's cells, which could cause an immune reaction in a transplant recipient. The concept, Weiss explained, is to use the patient's own stem cells to regrow new lung tissue, or even grow an entirely new lung using a 3D bioprinter. He called the technology, which is still in the early stages of development, "the ultimate in personalized medicine."

"If I remember correctly, this is from a lifelong nonsmoker, so it's a beautiful, pristine-looking lung," Weiss explained. "We get [donated] lungs from patients with emphysema, and they look nasty even when you take all the cells out."

As a pulmonary critical care physician at UVM Medical Center, Weiss spends about a third of his time seeing patients in the intensive care unit. The rest he spends overseeing what is considered one of the top three or four labs in the world doing research on pulmonary regenerative medicine. That's a broad term for therapies that repair tissues and organs that don't naturally heal themselves.

Weiss and his research team are trying to regrow complete lungs, or sections of lungs, that they hope will one day be used to repair or replace lungs damaged by disease. Central to that effort are stem cells.

"We're pretty far along," Weiss said. "Are we at the point where we can actually do it? Not yet."

Indeed, regenerating lungs has proven to be exceedingly difficult, he said. While more progress has been made in growing simpler human tissue, such as skin, muscle, bone and cartilage, "The lung is a tougher nut to crack."

Why? As Weiss explained, a normal human lung consists of about 40 different cell types. The challenge is to figure out how to assemble them, and in what order, using various nutrients and oxygen concentrations.

Longer term, the researchers hope to regrow and repair lung tissue within the body itself. In fact, if this and other stem cell research projects underway at UVM prove successful, Weiss envisions Burlington becoming a center for regenerative medicine, expanding the state's biotech economy.

On a tour of the lab, the physician lamented what he called "the dark side to regenerative medicine," or the marketing of unproven therapies and "stem cell medical tourism" around the globe.

Weiss couldn't comment on either of the stem cell clinics operating in Vermont, saying he doesn't know enough about the specific treatments and procedures they offer to assess their effectiveness.

As chief scientific officer for the International Society for Cell & Gene Therapy, however, Weiss serves on a task force on the use of unproven or unethical cell and gene therapies. Later this month he's expected to testify as an expert witness in a lawsuit against an out-of-state stem cell clinic; Weiss declined to identify which one, except to say that it's not affiliated with those in Vermont.

In mid-October, the International Society for Cell & Gene Therapy hailed an Federal Trade Commission crackdown on two California-based companies that were making deceptive and unfounded medical claims. Specifically, the companies claimed that their "amniotic stem cell therapy" could cure serious diseases such as Parkinson's, macular degeneration, cerebral palsy and autism.

The FTC's action came on the heels of last year's announcement by FDA Commissioner Scott Gottlieb that his agency would be stepping up its oversight of the industry's worst offenders, beginning with warning letters sent to clinics whose off-label treatments had harmed patients. While Weiss hailed that measure, he said that even more enforcement and oversight are needed.

One problem, Weiss noted, is that less reputable stem cell clinics have begun recruiting patients through ClinicalTrials.gov. The website, operated by the National Institutes of Health, ostensibly recruits patients for legitimate research studies on diseases and conditions.

But last year, the American Academy of Orthopaedic Surgeons warned that the site has been "hijacked" by some stem cell centers advertising studies that have not received institutional review board approval, have never published their results in peer-reviewed journals and conduct "patient-sponsored" research — coded language indicating that the "studies" require patients to pay in cash to participate.

"Unfortunately," Weiss said, "regenerative medicine has taken on a significant aspect of snake oil."

Offshore Solutions

"There's a lot of fraud out there, which is kind of scary," agreed Dr. Jonathan Fenton, a doctor of osteopathy at Vermont Regenerative Medicine in Winooski. He and his partner, Dr. Evan Musman, provide what they call advanced stem cell and platelet-rich plasma procedures to patients with joint injuries and degenerative disorders.

Fenton, who's been practicing in Vermont for about 25 years, first got involved with Regenexx in 2014. Like Stem Cell Centers of Williston, Regenexx is a national organization that markets directly to consumers through newspaper ads and free informational seminars, including several that were held in Shelburne in the spring.

As Fenton explained, most of the patients who come to him are trying to avoid knee, hip or shoulder replacement surgeries. He also treats "a lot of ACL tears" and claimed that, if any fibers remain in the ligament, "we can regenerate them."

On the day he spoke to Seven Days, Fenton said he'd treated cases of ankle and knee arthritis, tendon tears, rotator tears, and plantar fasciitis, "orthopedic conditions that are usually treated [in hospitals] with either bracing or hope."

Every three months, Fenton flies to the Cayman Islands, where Regenexx can "culture expand" patients' stem cells by extracting them from the pelvis, growing them in a petri dish, then injecting the higher concentration of cells back into their bodies. According to Regenexx literature, this procedure yields "100 to 1,000 times more stem cells" than those done in the U.S.

"It works better," Fenton argued, "but it's not allowed here."

Here's why. In 2010, the U.S. Department of Justice sued Regenexx Sciences of Colorado, alleging that, among other things, the procedure violated federal laws and the company hadn't performed adequate studies on its safety or effectiveness. In 2012, a federal judge issued a permanent injunction preventing the procedure from being done in the United States.

So Regenexx set up shop in the Cayman Islands, where, according to its glossy pamphlets featuring golfers, runners and volleyball players, patients can get their treatments on day one, then begin their "pain-free future" on one of the world's top-ranked beaches.

Some patients rave about their results. In March, at a free informational seminar that Vermont Regenerative Medicine put on in Shelburne, a woman in the audience recounted her experience with a Regenexx procedure to treat a rotator cuff injury.

"I don't like needles, and the first time, I thought I was going to die," she told a crowd of about 40 people. "But once I realized the benefit, I was blown away ... Honest to God, I would do it again in a heartbeat."

"You're a plant, aren't you?" joked Musman, Fenton's partner at Vermont Regenerative Medicine.

But others in the audience seemed skeptical, including one man who asked why the FDA won't allow the Regenexx procedure to be done in this country.

"If you feel that the data is so strong," he asked, "why is [your stem cell therapy procedure] not the standard of care?"

"The surgical lobby ... and medical device makers are a strong lobby, and they have a lot of money," Musman said. "A lot of it is the big medical-industrial complex that is slow to change, because the data is incontrovertible."

When Fenton was asked whether any controversy surrounds his work, he too suggested that clinics such as his face resistance from the medical establishment because they undermine the financial stability of surgical and orthopedic units.

"It's controversial because it's a threat to the current paradigm. But the safety studies are amazing," Fenton insisted. "The complication rate is practically zero." Seven Days couldn't independently confirm that claim.

Vermont Regenerative Medicine didn't respond to follow-up requests by Seven Days to provide the names of other Vermont patients who might speak about their experiences with Regenexx procedures.

Fenton isn't just a Regenexx practitioner; he's also a client. After breaking his hip in a skiing accident several years ago, Fenton had a Regenexx procedure performed on himself; he claimed it allowed him to avoid surgery. After three years, he had the procedure repeated on the same hip, which he predicted would provide him relief for another five years.

"I want to move things forward, which is really difficult in this town," Fenton said. "The paradigm is very hard to shift, unfortunately. It's very sad."

Wheat and Chaff

How does a patient with little or no scientific training assess the claims of stem cell providers?

At the Holiday Inn seminar, the Stem Cell Centers' Wolther told potential patients that injecting stem cells into their bodies could "regrow cartilage and ligaments and tendons and meniscus" and "repair and regenerate disc material in our spines."

Has stem cell therapy advanced to the point where it can regenerate the discs in a person's spine?

"No, there's certainly no evidence of that," said Dr. George Muschler, an orthopedic surgeon and stem cell researcher at the Cleveland Clinic Lerner Research Institute in Ohio. Muschler, a colleague of Weiss' in the International Society of Cell & Gene Therapy, runs a laboratory that develops and tests new stem cell therapies for patients suffering from musculoskeletal issues such as bone fractures, cartilage damage, arthritis and osteoporosis.

"On a case-by-case basis, I can't say that an individual patient won't benefit from these therapies," he said. "But one patient doesn't make for a generalized rule."

As Muschler explained, there's a large financial incentive for practitioners with some medical credential — who perhaps have never done stem cell research and who may not even be experts in the diseases they're treating — to buy a centrifuge and open a stem cell therapy clinic.

"And a lot of patients will show up," Muschler went on. "The challenge is, how do you separate the wheat from the chaff? How do you figure out who is a legitimate player and who is an opportunist? Or a charlatan?"

At the nonprofit Cleveland Clinic, Muschler and his team have taken a creative approach. When stem cell clinics began appearing in the area, his group began offering some of the same services, but with a difference. His doctors gather data from treating patients and study the results, hoping to reach conclusions about the effectiveness of stem cell therapy. Patients pay less than at for-profit clinics.

His practitioners measure the patients' performance before receiving the therapy, using metrics and objective numbers, then assess those patients six months later and ask them to be "painfully honest" about how they're doing. The Cleveland Clinic also has a medical ethicist on staff to ensure that it doesn't overpromise results.

"We partner [with patients]," Muschler said. "We tell people, 'If this works, we want you to tell us. And if this doesn't work, we want you to tell us.'"

Finally, he said, he and his team will publish their results in peer-reviewed journals, with the understanding that stem cell therapies are still in their infancy.

As Muschler tells his patients, "If you're coming here, it's not because we think we have magic. It's because we're committed to studying this so that your kids and grandkids will know the real answer. Because the truth is, right now, we just don't know."

Grand Gift Ideas for a Holiday Shopping Head Start | killexams.com real questions and Pass4sure dumps

With Black Friday and Cyber Monday looming, many are already strategizing how to take advantage of the throngs of deals and steals to be had. And online shoppers are poised to make an indelible mark given their collective spending power—a retail category that’s demonstrated exponential growth year after year. According to Statista, around $72.3 billion was spent online in 2017 alone, a staunch increase from the $29 billion spent in 2009. But as online shopping burgeons, it also overwhelms amid a glut of consumer goods all vying for your eyeballs, hearts, minds and wallets. So, to help streamline your shopping and reduce your stress in kind, I’ve curated this range of holiday gift ideas across various product categories ensuring there’s something for everyone on your “nice” list.


Viotek’s GN34C Ultrawide QHD Monitor (www.Viotek.com) 

The Viotek GN34Cx is a multitasking workhorse display—an ultrawide 34-inch monitor combining top gaming specs with the reliability of a professional business monitor. View flicker-free video with superior color reproduction, finalize media-rich office projects, and dominate FPS/RTS games. With the GN34Cx, every detail comes to life in ultra-wide QHD (3440x1440p) clarity–two and a half times the resolution of other full HD monitors. The 100Hz monitor refresh rate offers critical precision and accuracy when it matters most–during graphically demanding applications and action-packed games. The GN34Cx’s natural 1800R curve matches the natural curve of the human eye and renders game environments more realistic. Through AMD FreeSync technology, each frame and every movement are clear and smooth, even during CPU-intense, action-packed games, which prevents ghosting or tearing. With amazing edge-to-edge ultrawide QHD clarity, the GN34Cx is a value-centric PC computer monitor.

Crazybaby Air Nano Wireless Earbuds (www.CrazyBaby.com - $20 off with promo code “CRAZY20OFF” through December 2018

The Air Nano Wireless Earbud by Crazybaby is a great gifting option and a perfect stocking stuffer. The classic bullet design of these wire-free earbuds offers a snug fit for all types of ears, making them perfect for running, jogging and other rigorous activities. The soft material that makes up the wingtip is water-washable, anti-static and removable (different size options come bundled). It uses the industry’s leading 998 custom-made Carbon Nanotube Diaphragms, enabling crystal-clear acoustics that facilitate an immersive music listening experience. The boast eight to 12 hours of playback time for all day use. Super fuel technology allows a quick five-minute charging window for a full 90 minutes of playback. Precision engineering has resulted in an ultra-compact charging case design that can fit in any of the smallest pockets without worry about cables tangling up. The Crazybaby air Nano Wireless Earbuds are available in 10 trendsetting and vibrant colors with plenty of choices to match your personal style.

Circle Home Screen Time Controller (www.MeetCircle.com) 

Circle Home is a smart solution letting families of all sizes monitor and filter screen time across all devices, both inside and outside the home. It sets up seamlessly to your Wi-Fi network, and, through its intuitive app-based dashboard, parents can create unique profiles for each family member with specific parental control settings. These include Time Limits – allowing for complete control of screen time usage between a variety of apps, platforms and web-based programs (like Snapchat, Instagram, Facebook, YouTube and more); Bedtime – automatically disconnecting and reconnecting devices from Wi-Fi at scheduled times; Filter – setting individual age and interest filters for each family member; and Pause – having the ability to turn on and off network Wi-Fi at any time. Imagine a world with only 30 minutes of social media per day! Circle takes the fighting out of screen time and empowers parents to set and follow through on their expectations around the house. You can even opt for service off of your own Wi-Fi network as well, ensuring full control no matter where your child may be.

Playground Sessions Keyboard/Piano Lessons Bundle (www.PlaygroundSessions.com) 

Give the gift of music and an enriched live by helping them learn how to play the piano at home. Playground Sessions, a company co-created by Quincy Jones, is passionate about using its innovative technology and musical expertise to help people improve themselves and enjoy life more. The bundle includes a Casio CTK-2090 keyboard, which is compact with 61 piano-style keys. It’s a great entry keyboard for the beginner player. In addition to the CTK-2090 keyboard, the Playground Sessions bundle includes a keyboard stand, Audio Technica ATHSJ11BK Portable Headphones (White), Hosa GPM103 3.5mm (F) To (M) Stereo Adapter, an On Stage KSP20 Universal Sustain Keyboard Pedal, a Power Supply and a USB cable to connect to Playground Sessions online instruction via your computer or iPad.

Sharkbanz Shark Attack Deterrent (Sharkbanz.com) 

This next travel product is a real lifesaver, literally! It’s Sharkbanz, a convenient shark deterrent for the beachgoer, swimmer, and surfer. Created by surfers and divers and tested by marine biologists on predatory shark species, Sharkbanz uses patented magnetic technology to interfere with sharks' sensitive electroreceptors. Sharkbanz doesn’t harm sharks or other sea creatures, use no batteries, require no charging, and are designed to endure rigorous water sports. And, $1 of every Midnight-Bimini Sharkbanz design sold benefits the warrior surf foundation—a surf therapy organization for veterans.

VocoPro Pop-Up Oke (www.VocoPro.com) 

Here’s a great gadget gift for singers who would enjoy a fun, all-in-one wireless karaoke mic with a built-in mixer/speaker, complete with its own light show! From audio leader VocoPro, the Pop-up-Oke microphone can connect to a smartphone or tablet via Bluetooth and use YouTube or any number of different karaoke apps to access and enjoy hours of entertainment. Singers can also use the onboard MP3 SD/TF player to perform with recorded MP3 tracks. The multi-color LED lights can be turned on or off and, when on, will automatically “dance” to the beat of the music to add a visual excitement to any karaoke session. The system features a new generation of wireless karaoke microphone technology, including an all-in-one portable design. It’s just perfect for small karaoke gatherings and road trips! it also features innovative music link technology that can pair two Pop-up Oke devices to perform duets, a shock-mounted professional condenser microphone to reduce handling noise, and a user-replaceable lithium ion rechargeable battery (type 18650).

ChargeHub Powerstation 360 Surge Protector Power Strip (www.LimitlessInnovations.com) 

Here’s a practical gift item that any device devotee with appreciate: the ChargeHub Powerstation 360, billed as the most efficient charging station on the market today. It features quick and convenient charging for up to 10 devices simultaneously, including four USB’s, six AC Outlets, and provides up to 4000 joules of surge protection with a lifetime connected equipment warranty. The ChargeHub 360 is designed with a safety power-surge to protect all gadgets and devices while providing the optimal charge. It uses patented SmartSpeed Technology to provide an optimal charge for virtually any device, up to 2.4 Amps per port or five Amps overall. The six AC outlets (125V / 10A / 60Hz / 1250W) positioned in a circular pattern provides more space between each outlet to maximum functionality. The strip also includes: a 6-foot heavy-duty power cord with a 90-degree plug and protected/grounded LED indicator lights. The textured finish is also scratch-resistant and it’s wall mountable so it is easy with the provided screws, hanging template, and instructions – a perfect fit for any home, office, dorm room, workshop, and more!



William Henry Luxury Jewelry & Accessories (www.WilliamHenry.com) 

Those looking for a truly wow-worthy jewelry gift should look no further than William Henry, an American luxury brand for men and women that crafts unique artisan collections that include jewelry, writing instruments, money clips and award-winning pocketknives enjoyed by A-listers like Harrison Ford, Laurence Fishburne, Luke Bryan, and Cameron Diaz, among many others. William Henry is revered for its painstaking use of precious metals, minerals, and unusual organic materials, and they’re celebrated for their meticulous hand-finished craftsmanship and details. The company often unveils new designs, which most recently includes its bold and distinctive new “Embrace” collection for men and women boasting an array of extraordinary jewelry pieces with signature caged design aesthetics. This includes the Embrace Wisdom pendant featuring a beautiful natural South Sea pearl ensconced in 18 karats rose gold on a finely stitched leather cord, also with William Henry’s “arrow” toggle clasp in sterling silver. The tones play off each other, resulting in an alluring nuance and warmth. For guys, the “Ardent” design, William Henry’s only all-sterling necklace, takes their smallest classic link that’s configured as a chain. Simple but distinctive, lightweight but substantial, it makes a great personal statement. For men or women, I also love the William Henry Bolt Maui Pen made from fabled curly Hawaiian Koa wood. It’s substantial, yet elegant enough to carry and use comfortably. Sleek and elegant, this pen boasts modern mechanics, clean lines and timeless craftsmanship designed to command any room and make a strong statement.

Offero Handbags (www.OfferoHandbags.com) 

Sourced from the finest Italian leather, Offero Handbags are inspired by strong, confident and empowered women, designed to protect your belongings, while creating the life you want to lead. A woman-owned and managed company, Offero brings you American-made ultra-femininity with built-in patent pending anti-theft features. This includes Twaron slash-proof fabric, Radio-Frequency Identification (RFID) shielding interior pockets to prevent identity theft, and combination lock technology. The Offero line boasts three different styles, each with two separate colorways: "The Miami" (metallic silver/navy and copper/ivory), "The Manhattan," (black and caramel), and "The LA" (cobalt and blush), all featuring Offero's brilliant signature emerald green interior. The "Miami" design uses special water-resistant Italian leather exterior and nylon interior to help protect your precious belongings from the rain or a day at the beach, because let's face it sometimes life is unpredictable. The fabrics utilized in Offero products are reportedly five times stronger than steel—actually the same material used in body armor. Not even an X-ACTO knife or box cutter will be able to get through to your valuable belongings. And they’re certainly secure as Offero uses a patent pending combination lock technology on the shoulder strap of all of their products; so women can safely lock their bags in crowded areas. Detachable chain straps allow you to wrap the chain around a chair as you enjoy your meal at a crowded restaurant without having to worry that someone will slip your bag away from you. Also cause-minded, a portion of all proceeds going to disaster relief efforts.

SLATE COLLECTION Leather Goods (www.slatecollection.com) 

SLATE COLLECTION is a new line of meticulously-crafted top-quality leather products that not only inspire, but also perform and endure. With great leather sourced from the American Midwest as the foundation, SLATE COLLECTION products feature thoughtfully-designed elements that make them practical, inspired and perfect for work, home and travel. The line includes a range of stylish products hand-crafted by artisans who use time-honored, exacting techniques, including totes, wristlets, journals, travel accessories and a tech collection—all in carefully chosen signature colors such as indigo, cognac and midnight.  You just can’t go wrong with classic gift items like their elegant Elliot Bay Folio made from full-grain, water-resistant leather with two sides for holding a legal pad and single sheets of paper with corner pockets. It’s great for staying organized in the office or on-the-go.  Personalization is even available on the paper. The Sand Point Passport Holder is another great gift option. Also made from full-grain, water-resistant leather, this sophisticated design with 4 pockets holds a passport and cards tightly and securely. It’s great for the non-stop jet-setter.  Monogramming is available on this item and other select SLATE COLLECTION products.

VALIMOR Caliburnus Hand-Tooled Automatic Watch (www.Valimor.com) 

Here’s a timepiece that combines the old and the new: the Valimor Caliburnus Hand-Tooled Automatic Watch. Inspired by the legendary Sword in the Stone, this unique timepiece features dragon scales on the solid bezel and swords for dials, making it reminiscent of ancient armor. Featuring jewel-grade natural stones, the patented design features a rich texture that’s one-of-a-kind in pattern, texture, color, and personality—no two timepieces are alike. Plus, it uses Swiss SuperLumiNova BGW9 pigments for the lume on the watch hands, ensuring full visibility in the dark. This distinctive watch, available in various colorways, is ideal for collectors, watch lovers, and fashion-minded men, alike.


Anemela Official Women's Fashions (www.Anemela.com) 

One of my favorite finds of the season is the renowned women's fashion site, Anemela Official--a one-stop-shop for top brand clothing, swimwear, dresses and accessories. This online store offers tons of top-quality products for any occasion. Are you ready to go for coffee, drink, at the gym, for a walk, on a date, wedding or for clubbing? Do you have a business meeting or job interview to go to? Have you planned for a trip to the beach, mountains, or other vacation? Or do you want to cozy up at home? No matter where you want to go or what you want to do, Anemela.com will have you covered because they believe "every woman deserves to feel the fashion spirit at any moment." There are over 20,000 women's products that fit in any body shape and size, so Anemela.com is sure to have you covered in fabulous style. Plus there's free shipping on all orders!

Sevenly Statement Apparel (www.Sevenly.org) 

Sevenly is an online cause activation marketplace that offers fashionable clothes for the whole family that also make a statement. This is thanks not only to their eye-catching designs, but also because each item contributes to heroic non-profit organizations. For example, their Autism Community Collection features a wide array of bold graphic tees, jewelry and sweatshirts that help the Autism Society provide advocacy, education and support to families effected by Autism. The Autism Community “Dare to Be Different” t-shirt in particular, provides funding toward resources and support to families in the Autism Community. Whether increasing awareness for Breast Cancer and Parkinson’s Disease, or promoting women's empowerment and anti-bullying, each cause-collection features a wide array of cause-conscious benefits.

TruCulture Clothing Co. Leather Apparel (www.TruCulture.com) 

TruCulture Clothing Co. makes apparel for strong women with a passion for life—and those like me who love fine leather garments with a street glam edge. Their unique, premium-quality designs boast supple, hand finished leathers. One of my personal favorites is their Distressed Ruby Multi Buckle Leather Jacket that’s hand processed for a vintage look. It’s loaded with metal zippers, buckles and seaming for the perfect fit. Bright red in color, it’s a real attention getter so be prepared to turn heads. I also absolutely adore the cognac-colored Street Glam Corset Multi-Ties Leather Jacket, which has a distressed wash and finish with various ties, snaps and an elbow-length invisible sleeve zipper that also ensures a great fit. From jackets like these to tops, bottoms and jewels, TruCulture Clothing is bold, classy, glamorous, sexy and empowering. Plus, it’s versatile enough to be worn from the work day on into date night. TruCulture was born in January of 2012 by sisters Claudia and Tommasina Tiberio, both avid motorcycle riders who’ve designed a chic clothing brand that helps women exude confidence with every step.

Basic Outfitters Create-a-Drawer for Men (www.BasicOutfitters.com) - Free shipping with code ‘LuxeList’  The married entrepreneurs behind Basic Outfitters came up with their flagship Create-a-Drawer service to solve a problem that so many men face. Seen on ABC’s Shark Tank, the product is perfect for the guy who refuses to clean out his sock and underwear drawer. Basic Outfitters' Create-a-Drawer gives the guy in your life a customizable collection of high quality and fashionable essentials for an unbeatable value. Available in small, medium and large drawer options, Create-a-Drawer helps guys replace their old, worn out attire with a whole new wardrobe of socks, underwear, tees, joggers, hoodies, shirts and more quickly, easily and for an affordable price. This gift will get your man more organized than ever.

*****BEAUTY & SELF CARE*****

N:P Beautiful Flat Iron (www.NPBeautiful.com) 

Created by celebrity hairstylist David Babaii (the main man behind Kate Hudson's beachy waves), this sleek, modern iron can do far more than the norm. It has a curved to allow for endless styling options like waves, flips, curls and ringlets. Its innovative rose gold vibrating plates (which can be turned on or off) shuffle the hair back and forth to minimize tugging, slipping, or pulling. The iron has fast, even heating with instant recovery; a slim, ergonomic handle that closes firmly without strain; and provides a cool touch, no-slip grip for even pressure ensuring there are no uneven hot spots on the hair. The device also heats up to 400 degrees to maximize its effectiveness. As a cause-conscious company, 10 percent of the net proceeds go to support Pediatric Cancer Research and Animal Welfare causes.

Kiss My Lash Triangulated Mirror & False Eyelashes by GoodJanes Beauty (www.GoodJanes.com) 

Help those style-minded gals in your life take their look to the next level with GoodJanes Beauty’s natural, dramatic and glam styled lashes. With 18 varieties, each lash is handmade with cruelty-free, 100 percent mink fur collected from natural shedding. The lashes are stored in clear, protective trays and, with proper care, each lash can be reused up to 25 times. Another of the company’s products is Kiss My Lash, a novel triangulated mirror that lets you to see your upper lash line from above and below at the same time. The patented design provides the truest line of sight to get your falsies flush against the lash line on the first try! The mirror can be held in your hand, placed on a flat surface or attached to the magnetic, hands-free Kiss My Lash Stand.

Sonic Facial Deep Cleansing Brush (www.SuperDuperKiss.com) 

The Sonic Facial Deep Cleansing Brush is a stylish combination of quality, performance, ergonomics and convenience all packed into one efficient design. This effective facial brush for all skin types offers a complete cleansing experience. It has an IPX 4 waterproof design and was created with Acoustic Vibration Technology, proven to improve skin care, and has two-speed settings. This technology helps increase light makeup removal and deep cleansing, and significantly improve skin care problems (like blemishes and clogged pores) also improving skin elasticity and collagen production. It comes as a 3-in-1 Kit that includes a massager and exfoliator that vibrates an average of 6,600 movements per minute, which helps increase blood flow while decreasing puffiness and improving circulation—all without rubbing or pulling of the skin. The device relaxes muscles and tones, and also detoxifies the skin through lymphatic drainage (fluid) and exfoliation that removes dead skin cells.

Helmm Decorative Refillable Deodorant (www.Helmm.com) 

Helmm is a new antiperspirant and deodorant made with formulas that are paraben-free, phthalate-free and triclosan-free, which makes it good for your body. It’s also housed in a handsome high end-looking refillable container that’s not only good for the planet, but has a decorative look that makes it display-worthy. Helmm help upgrade your grooming game by offering a much-needed makeover on the old, plastic, single-use deodorant containers. With wonderful scents developed by a luxury French-perfumer, you won’t want to use your old stick ever again.

Wigs.com (www.Wigs.com)  Who doesn’t want to look fabulous and exude confidence, especially over the holiday? OK, I concede this might be a better “get”, but Wigs.com options are certainly giftable as well as they carry hundreds of wigs for women of all backgrounds—striving to make all ladies feel beautiful in this instantly wearable hair. Whether you’re looking for realistic human hair pieces, or pre-styled, ready-to-wear synthetic pieces, Wigs.com has comfortable options for every style and need. One option is the “Carrie” style by Noriko—a  medium length style with a balanced body. Evoking a romantic flair, Carrie is perfect for a chilly date night or even a cozy movie marathon. Be ready in an instant in this synthetic piece with its pre-styled waves that are sure to turn heads. There’s also the “Reese” style that’s a perfectly polished bob with sassy layers throughout. Get that classic look you’re going for with flippy ends and a sleek side fringe. Breathable, lightweight, and comfortable, Reese is perfect for the woman on-the-go and can be worn straight out of the box.  Gorgeous in an instant!


Little River Inn (www.LittleRiverInn.com)  For those who prefer experiential gifts or want to arrange a lovely holiday getaway, consider a stay to the Little River Inn—a family-owned and operated resort on the Mendocino coast of California. This picturesque property features a chef-driven restaurant and bar, a nine-hole Audubon-certified golf course, professional tennis courts and a day spa. Ideal not just for romantic getaways, it’s great for the entire family (and pet-friendly as well). The Inn has 66 guest rooms ranging from the economical to the more luxurious. Several private meeting and special event spaces with stunning ocean and garden views make the Little River Inn an excellent venue for small-to-medium-sized weddings and corporate retreats as well. The Little River Inn Restaurant, helmed by CIA-trained Executive Chef Marc Dym, offers hearty California coastal cuisine, and Ole's Whale Watch Bar is a classic hangout for guests and locals alike.

Paskho Travel Apparel (www.Paskho.com) 

Paskho clothing is a great new way to travel in comfort and style. The brand’s name comes from the ancient Greek word “passion,” and these sustainable pieces were created with that in mind. Paskho pieces for both men and women have impeccable details and luxury looking performance fabrics that are livable and pliable, but still fashionable. The garments are perfect for any excursion whether it's to your local corner store, a slope or sand dune around the globe. Paskho is built to suit the freedom-seeker and the maverick nomadic and the fearless observer, all together.

The Airhook for Air Travelers (www.TheAirHook.com) 

Give frequent air travelers a comfort upgrade with The Airhook. It’s a two-in-one solution for airplane travel comfort: a stable drink holder and a secure mount for an electronic device (cell phone or tablets 8.5 inches tall when horizontal). Designed to elevate the level of convenience by allowing for maximum legroom, The Airhook attaches to the tray table in its locked vertical position for use as an anchor, rather than needing to lay the tray horizontally across your lap as a platform. This way you can view your device and access your beverage unencumbered. Other features include: an adjustable angle accommodating for reclined seats and a better viewing posture, as well as a small hook for earbuds or to keep a light garment off the floor. It’s a great hands-free entertainment method for children. It’s also perfect for big and tall travelers and is collapsible for easy carry-on storage. It’s surely an easy way to make plane travel better, so you no longer need to sacrifice space with the folding down trays.

MyPhonePouch Cell Phone Carrier (wwwMyPhonePouch.com) - 15% off with code ‘ATLANTA’

Here’s a great way to help someone stop misplacing their phone and wasting valuable time looking for it! MyPhonePouch is a sleek, innovative solution allowing you to carry your cell phone securely and accessible on your hip. This soft, stretchy pouch is worn tucked over any snug, sturdy waistband to instantly add pockets to an outfit. Designed by Allison Santini, it’s especially great for those women and girls who often lack pockets in their outfits. It’s great with leggings, yoga pants, sweats, shorts, skirts, slacks and other pocketless garments. Made of high-density performance fabric, MyPhonePouch is available in different colors and sizes to fit most phones.

*****PARENTS & KIDS*****

Gerber Brand Essentials Clothing & Accessories Collection (www.Walmart.com) 

A great idea for new moms and moms-to-be is the Gerber Brand Essentials Collection available at Walmart this holiday season with pricing that fits any budget. If you’re a new parent prepping to bring home your bundle of joy or looking for baby’s first-holiday gift, this collection offers a wide assortment of baby clothing and accessories that are as cute as they are comfortable. This includes bodysuits and sleep n’ plays, to caps and socks in super adorable prints and patterns like pink bunnies, polka dots, outer space and safari.  All items in the Gerber Brand Essentials Collection are made with organically grown cotton that's breathable and soft for baby’s delicate skin, and easily transitions from playtime to bedtime. 

Just Born Infant Keepsake and Sparkle Collections (www.BuyBuyBaby.com) 

The Just Born Keepsake and Sparkle collection, available at buybuyBABY, offers beautifully packaged items perfectly giftable for any new mom or baby. Featuring nursery bedding, bath, accessories and décor, both the Just Born Keepsake and Sparkle Collections were recently refreshed with new colors and styles. This includes the on-trend Sparkle Collection rose gold 2-pack hooded towel and 4-pack washcloth sets, which add extra shimmer to baby’s beautiful moments. Designed with a European-vintage feel, the Keepsake Collection features pieces like this grey linen quilt, faux animal heads and plush bath items that are designed with delicate lace and embroidery details—a wonderful high-end (yet affordable) holiday gift.

Decorate an Ornament Kit & Paint by Number Barfing Beast Kit (www.KidMadeModern.com) 

These fun Decorate Ornament kits by Kid Made Modern are a great way to get your little ones into the gift-giving spirit. Each kit makes a one-of-a-kind keepsake that they can give to their grandparents, teachers, friends or the mailman. You can even collect all six to decorate your own tree. The Paint by Number Kit “Barfing Beast” is a modern approach to mid-century paint by number kits. Each one features vibrant colors and the playful illustrations made by Patrick Hruby and includes everything needed to complete the project.


Sci-Fi & and Fantasy Books by Michael Drakich (www.Amazon.com) 

Here’s a great gift idea today that doesn’t involve a screen or electricity to enjoy for a change! It’s fictional science fiction and fantasy books from author Michael Drakich. With titles like The Infinite Within, The Brotherhood of Piaxia, Grave Is the Day, Assassins of Riaz, I Am, Lest the Dew Rust Them, and Demon Stones, these thrillers offer hours of captivating adventure! As a highly rated author, top reviewers rave about the level of detail in Drakich’s storytelling, and imagination that seems to know no bounds. He’s lauded for taking readers straight into the minds of his characters, developing them into a riveting and extremely entertaining tales. You can check out Michael Drakich’s fictional science fiction and fantasy books for yourself at Amazon.com, Barnes & Noble, apple and more.

 “The Legacy Letters” Book by Carew Papritz (www.Amazon.com) 

A winner of five national awards (including the Mother’s Choice Award), “The Legacy Letters” by Carew Papritz helps people reconnect with family and friends again. The story reveals to the readers the rediscovered private letters from a dying father to his children–and to his wife. His words of wisdom, interwoven between deeply personal stories and poignantly-told memories, ultimately become the practical, moral and spiritual guidebook for his children that he’d unfortunately never live to see; and for his wife, his redemptive act of love. It’s easy to get caught up in our fast-paced, technology-driven society. This back-to-the-basics novel reminds people how to slow life down again, to be in the moment and remember what’s really important. Combining the best elements of various inspirational best-sellers such as “Tuesdays with Morrie,” “The Last Lecture” and “Chicken Soup for the Soul,” “The Legacy Letters” reads like a true-to-life story and is filled with timeless wisdom for the modern age.


Bag Branch Purse Organizer (www.BuyBagBranch.com) 

The averages person wastes 2.5 days a year looking for stuff and I, for one, am guilty as charged. That’s a mini vacation! People waste precious time searching and digging in their bags, so Bag Branch is a giftable solution unlike any other. It’s an accessory that holds your daily essentials—the items you reach for many times a day—like glasses, phone, keys, cards, pens, gum, etc., keeping these daily essentials together and accessible at your fingertips. It ensures these items are easy to take out and put back where they belong. Plus, you can easily change bags in one easy move, also knowing that you won’t leave your most important things behind. It fits in almost all sizes and shaped bags, structured or not. This patent-pending design features wide and structured pockets that don’t collapse when empty.

Barley+ Bars (www.BarleyPlus.com) 

Barley+ bars are a healthy stocking stuffer option versus all of that candy that normally bloats those holiday stocking—and the recipients that partake. These delicious and nutritious bars are made with a unique type of Barley called BARLEY MAX that has more soluble fiber, insoluble fiber and resistant starch than other grains. The results taste and feel amazing because Barley Plus contains Pre-biotic dietary fiber to help feed the intestinal flora, so it’s great for gut health.


***Some or all of the accommodations(s), experience(s), item(s) and/or service(s) detailed above may have been provided at no cost or sponsored to accommodate this review, but all opinions expressed are entirely those of Merilee Kern and have not been influenced in any way.***


One-to-One Laptop Initiatives Boost Student Scores, Researchers Find | killexams.com real questions and Pass4sure dumps

Chromebooks-Montgomery-County-classroom-blog.jpgBy Leo Doran and Benjamin Herold

Efforts by K-12 schools to give every student a laptop computer increased student achievement and gave a modest boost to their "21st century skills," according to a first-of-its-kind meta-analysis of 15 years' worth of research studies.

"It's not like just providing a laptop to every student will automatically increase student achievement, but we find that it's the first step," said Binbin Zheng, an assistant professor of counseling, educational psychology, and special education at Michigan State University.

Using statistical techniques to analyze already-completed studies, Zheng and her colleagues found that 1-to-1 laptop programs on average had a statistically significant positive impact on student test scores in English/language arts, writing, math and science. The limited number of rigorous quantitative studies available to analyze mean that those findings are not definitive, but they are clearly a good sign for 1-to-1 proponents and underscore the need for more study, Zheng said.

A further review of 86 additional papers by the researchers, meanwhile, found some modest evidence of other positive benefits associated with giving laptops to students, including increased student technology use; more student-centered and project-based instruction; greater student engagement; and better relationships between students and teachers.

The analysis focused solely on 1-to-1 laptop efforts. The researchers cautioned that their results are not generalizable to other devices such as tablets, desktop computers, and smartphones.  

The new findings run counter to the skepticism about educational technology expressed by many researchers and practitioners. A raft of prior studies, for example, have shown that even when technology is present in classrooms, teachers are slow to transform their practice, instead using technology primarily to make administrative tasks and existing forms of instruction more efficient.

The new analysis has the potential to reshape the debate about ed-tech's impact, said Elliot Soloway, a computer science professor at Michigan University who has spent decades studying classroom technology.

"This is one of those definitive studies that comes along every 20 years," Soloway said. "Schools are going to use [the findings] to justify the move to 1-to-1."

Rapid Growth of 1-to-1 Student Computing

One-to-one student computing was first introduced to K-12 schools in the United States in the late 1990's. In 2002, Maine became the first state to launch a statewide program.

The trend has since gathered steam: In 2013 and 2014 alone, schools purchased more than 23 million laptops, tablets, and Chromebooks for use by students and teachers in the classroom (and sometimes at home.)

Generally, the goal is to enable teachers and software to deliver more personalized content to students, to boost students' technology skills, and to empower children to do more complex and creative work.

A handful of high-profile 1-to-1 disasters resulting from poor purchasing plans, bad planning, and a lack of clear academic vision have raised questions for schools about the wisdom of the approach, however.

And some research has been less than encouraging. A 2009 survey by the National Center for Education Statistics, for example, found that classroom technology was used for practice of basic skills far more often than for design and creation. A recent study by the Organization for Economic Cooperation and Development found that countries where 15-year old students use computers most in the classroom scored the worst on international math and reading tests.

In an attempt to definitively determine the impact of K-12 1-to-1 initiatives, Zheng and her colleagues reviewed 96 journal articles and doctoral dissertations published between January 2001 and May 2015.

Just 10 of those studies met the researchers' criteria for inclusion in the statistical meta-analysis of 1-to-1 laptop initiatives' impact on student achievement, reflecting the still-very-limited research base on student computing initiatives.

"A disproportionate amount of the research to date on this topic consists of small case studies in one or a handful of schools," Zheng and her colleagues wrote in their study, titled "Learning in One-to-One Laptop Environments: A Meta-Analysis and Research Synthesis," published online earlier this year in the academic journal Review of Educational Research. 

Still, there were enough historical findings to conclude that 1-to-1 laptop programs helped improve students' academic achievement by an overall effect size of .16 standard deviations—a figure that Zheng said indicates statistical significance, but is noticeably less than the effect sizes of other established interventions, such as small class sizes or individual tutoring.   

The researchers found the following effect sizes for specific subjects:

  • English/language arts, by .15 standard deviations
  • Writing, by .20 standard deviations
  • Math, by .17 standard deviations
  • Science, by .25 standard deviations.
  • Reading, by .12 standard deviations
  • The impact on students' reading achievement was positive, but not statistically significant. Only two studies included science results that could be analyzed.

    The results are "small but noteworthy," Zheng said.

    Measuring Impact Beyond Test Scores

    The researchers also looked beyond test scores, reviewing 85 additional studies that did include an empirical examination of 1-to-1 laptop initiatives' impact in K-12 schools, but did not include an experimental design and/or quantitative results.

    Among the findings from that review: 

  • A 1-to-1 laptop environment often led to increased frequency and breadth of student technology use, typically for writing, Internet research, note-taking, completing assignments, and reading.
  • Students used laptops extensively throughout the writing process, expanding the genres and formats of their work to include writing for email, chats, blogs, wikis, and the like.
  • Student-centered, individualized, and project-based learning appeared to increase in at least some instances of 1-to-1 laptop rollouts.
  • Student-teacher communications (via email and Google docs, for example) and parental involvement in their children's school work increased in some instances.
  • Students expressed "very positive" attitudes about using laptops in the classroom, as findings consistently showed higher student engagement, motivation, and persistence when laptops were deployed to all students.
  • Students' technology and problem-solving skills improved and their ownership of their own learning increased, according to some evidence.
  • There were mixed findings on whether 1-to-1 laptop programs helped overcome inequities among students and schools.
  • Those results should be interpreted with caution, the researchers said, because they tended to rely on observation, survey, and interview data.

    "There was a wide consensus in the studies we reviewed that use of laptops promotes 21st-century learning skills," the authors wrote. "However, studies rarely attempted to operationalize and systematically measure the growth of 21st-century skills in laptop students compared with control students."

    Leslie Wilson, the CEO of the One-to-One Institute, a nonprofit that consults with schools and districts, said she was "thrilled" to see the new research, though she cautioned that educational leaders shouldn't leap to conclude that going 1-to-1 is enough on its own to increase student achievement.

    For such a program to be effective, she said, schools must focus on crafting comprehensive plans that cover everything from infrastructure to curriculum to pedagogy to professional development.

    And the real benefits of giving every student an access to a computer, contended Soloway of the University of Michigan, come when school move from "instructive" to "constructive" learning, or from "teaching kids to remember something to teaching them how to figure something out."

    To best measure the extent to which that change is taking place, Zheng said, researchers and educators will have to look beyond standardized test scores.

    Hopefully, she said, the new research will prompt further effort to develop assessments for students' digital literacy skills, as well as their creativity, independence, and leadership.

    "Many of the benefits of 1-to-1 laptop programs are not detected by standardized tests," Zheng said. "For the many programs whose purpose is to help students be a better 21st-century citizen, we need to develop and use corresponding measurements."

    Students at Ridgeview Middle School in Gaithersburg, Md. use laptops in class in 2014. --T.J. Kirkpatrick for Education Week

    See also:

    Follow @BenjaminBHerold for the latest news on ed-tech policies, practices, and trends. 

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    zoho.com : https://docs.zoho.com/file/5psib53d687fa7b714011853b5975ea329688

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    RES ES0-002 Exam (RES Wisdom 2009 Basic) Detailed Information


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