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000-080 System x Sales Fundamentals V7

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000-080 exam Dumps Source : System x Sales Fundamentals V7

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IBM IBM System x Sales

IBM (IBM) Outpaces stock Market features: What you should understand | killexams.com real Questions and Pass4sure dumps

IBM (IBM) closed the most recent buying and selling day at $116.67, affecting +0.49% from the archaic buying and selling session. This movement outpaced the S&P 500's each day gain of 0.01%. in the meantime, the Dow received 0.35%, and the Nasdaq, a tech-heavy index, delivered 0.45%.

Heading into these days, shares of the know-how and consulting trade had lost 3.5% during the last month, outpacing the laptop and technology sector's loss of 5.fifty one% and the S&P 500's lack of 7.29% in that time.

Wall highway might live attempting to find positivity from IBM as it procedures its next earnings report date. here's expected to live January 17, 2019. On that day, IBM is projected to record earnings of $4.eighty five per share, which might symbolize a yr-over-yr decline of 6.37%. in the meantime, the Zacks Consensus evaluate for income is projecting net revenue of $21.77 billion, down three.45% from the yr-in the past length.

looking on the complete year, their Zacks Consensus Estimates bespeak analysts are expecting income of $13.eighty one per share and profits of $79.56 billion. These totals would mark changes of +0.07% and +0.fifty three%, respectively, from ultimate year.

it's additionally crucial to live watchful the coincident adjustments to analyst estimates for IBM. These revisions typically reflect the latest short-time era trade traits, which can exchange often. as a result, they are able to interpret advantageous evaluate revisions as a superb mark for the company's enterprise outlook.

research shows that these evaluate revisions are without retard correlated with close-term share expense momentum. investors can capitalize on this through the exercise of the Zacks Rank. This mannequin considers these evaluate alterations and offers a simple, actionable rating gadget.

ranging from #1 (amazing purchase) to #5 (powerful promote), the Zacks Rank system has a confirmed, outdoor-audited track list of outperformance, with #1 shares returning an unconcerned of +25% yearly when you reckon that 1988. over the last month, the Zacks Consensus EPS evaluate remained stagnant. IBM at present has a Zacks Rank of #2 (purchase).

taking a inspect at its valuation, IBM is retaining a ahead P/E ratio of 8.four. For comparison, its industry has an ordinary ahead P/E of eight.67, which potential IBM is trading at a reduction to the group.

investors should silent too keep that IBM has a PEG ratio of 1.sixty nine at the moment. This generic metric is comparable to the commonly-usual P/E ratio, with the change being that the PEG ratio additionally takes under consideration the business's anticipated salary growth expense. IBM's industry had a conventional PEG ratio of 1.69 as of the day gone by's close.

The computing device - built-in systems trade is a portion of the laptop and expertise sector. This industry at present has a Zacks trade Rank of 102, which puts it within the properly 40% of outright 250+ industries.

The Zacks trade Rank gauges the energy of their trade corporations by using measuring the standard Zacks Rank of the particular person stocks in the organizations. Their research suggests that the privilege 50% rated industries outperform the bottom half with the aid of a factor of 2 to 1.

make inescapable to compose the most of Zacks. Com to comply with outright of these stock-moving metrics, and greater, in the coming trading periods.

desire the latest thoughts from Zacks investment analysis? today, that you may down load 7 most efficacious stocks for the next 30 Days. click to salvage this free file overseas company Machines organization (IBM) : Free stock analysis report To read this article on Zacks.com click on here.


IBM, Nvidia companion On modern Converged Infrastructure Optimized For AI | killexams.com real Questions and Pass4sure dumps

IBM Tuesday expanded its achieve into the burgeoning synthetic intelligence market with the introduction of a brand modern converged infrastructure appliance marrying its all-flash storage technology with high-performance GPU-based mostly servers from Nvidia.

large Blue's IBM SpectrumAI is a brand modern reference architecture optimized for AI workloads, talked about Eric Herzog, chief advertising officer and vp of international storage channels for IBM's storage division.

The IBM SpectrumAI is targeted at modern markets just starting to open up for channel partners, Herzog informed CRN.  

[Related: IBM Doubles Down On Flash, NVMe As It Commits To Taking Storwize 100 Percent Through Channel]

These consist of independent riding, place-based promoting, manufacturing exceptional and assurance evaluation, scientific drug trials, genomics, drilling exploration sensor analysis, customer sentiment evaluation and extra, he said.

the modern converged infrastructure for synthetic intelligence workloads brings channel partners a finished strategy to the AI statistics pipeline, Herzog spoke of.

"it is extensible and composable, and might span the records pipeline from ingest to archive," he observed.  

best of all, Herzog said, the IBM SpectrumAI will recede to market one hundred percent by artery of indirect earnings channels.

The IBM SpectrumAI isn’t IBM's first foray into providing a converged infrastructure platform on which to Run AI workloads.

IBM in June brought its first AI-based reference structure, but it mixed IBM's FlashSystem all-flash storage with the company's energy-primarily based servers, making it an all-IBM providing, Herzog pointed out.

the primary storage supplier to confederate with Nvidia turned into Mountain View, Calif.-primarily based absolute Storage, which in April delivered AI-able Infrastructure, or AIRI, which mixes its all-flash FlashBlade storage with Nvidia's DGX-1 GPU-primarily based platform and Arista networking. The trade in may additionally adopted up with AIRI Mini, a lessen-cost edition featuring a lessen-can permeate entry configuration and the alternative of Cisco Nexus 9000-based mostly networking.

NetApp in August delivered its rival, the NetApp Ontap AI, which mixes NetApp's AFF A800 all-flash storage array with end-to-end NVMe efficiency, Nvidia's DGX GPU nodes, and 100-Gbit Ethernet switches from Cisco into a converged platform for AI workloads.  

Herzog pointed out that IBM has differentiated its AI-focused converged infrastructure offerings in a brace of methods, together with having the most potent offering in the market thanks to its power server line, as well as distinctive expense points for its Nvidia-based mostly edition.

IBM is too pleasing in its application stack for its IBM SpectrumAI, Herzog spoke of.  

The IBM SpectrumAI comes with Spectrum Scale, the business's scale-out file gadget designed for immense data analytics, he said.

alternatives consist of the addition of OBM Cloud kick Storage for prime-performance information archiving; IBM Spectrum discover, which makes exercise of metadata to manage facts; and IBM Spectrum Archive for archiving records to tape, he spoke of.

The IBM SpectrumAI is according to IBM's FlashSystem all-flash storage array with all-NVMe efficiency, giving it a throughput of one hundred twenty GBps in a rack and over 30 GBps sustained random examine in a 2U footprint.

valued clientele can scale the offering to up to nine Nvidia DGX-1 servers with up to 2 GPUs in a rack whereas scaling storage from a separate 300-TB node to as much as eight Exabytes of records, Herzog stated.

purchasers will embody the IBM Spectrum AI, and many will speak that it's about time that IBM offered such an answer, said Kevin Carrington, vice chairman of sales at Lighthouse computing device services, a Lincoln, R.I.-based mostly solution issuer and longtime IBM and Nvidia channel partner.

"consumers view the marriage of Nvidia GPU-based server technology with flash storage as fueling a mess of trade alternatives," Carrington informed CRN.  

Lighthouse laptop capabilities is already working with the IBM power-based synthetic intelligence platform within the fitness-care market, Carrington said. "This has really upshot a spring back into the step of vigor," he pointed out. "It made vigor horny once more."

no matter if power-primarily based or Nvidia-based, IBM's synthetic intelligence structures wield actual-world client requirements, Carrington pointed out.  

"AI is everywhere," he pointed out. "it live how we're drinking IT, and how the marketplace sees us as patrons. or not it's throughout us, and or not it's happening these days."


IBM's $34 billion crimson Hat acquisition got here after deal talks with Microsoft, Google, and Amazon, sources speak | killexams.com real Questions and Pass4sure dumps

When IBM introduced its $34 billion acquisition of pink Hat on October 28, the tech word turned into struck by means of the immense cost tag, in addition to its competencies to restore IBM's struggling cloud company. but because it seems, issues could gain long past plenty differently.

Microsoft, Google, and Amazon outright engaged in deal discussions with red Hat and seemed closely into an acquisition within the months and weeks earlier than crimson Hat struck a contend with IBM, in line with sources conventional with the deal.

As an open-supply software enterprise, pink Hat is strategic as a result of its popularity with builders. or not it's too is the largest commercial maker of the Linux working gadget. IBM desired the know-how to expand its hybrid-cloud challenge and to give its portfolio an area.

red Hat indicated in a public submitting on November 30 that three unnamed agencies regarded making bids apart from IBM. CNBC mentioned in October that Google had looked into buying crimson Hat. but Microsoft and Amazon's deal talks with crimson Hat haven't been up to now suggested.

crimson Hat's shareholders will vote on no matter if or now not to accredit IBM's present on January sixteen, 2019. The deal may live the largest acquisition in IBM's one hundred-year-plus heritage and would straight catapult IBM into the properly ranks of cloud providers, a fast-turning out to live trade it truly is long been the domain of Amazon and Microsoft.

red Hat rejected IBM's first present

the primary spark of an IBM-pink Hat merger began at an April lunch between IBM CEO Ginni Rometty and purple Hat CEO Jim Whitehurst, according to remarks Rometty made at the time of the deal.

though IBM finally made a successful present of $190 a share, it took some negotiation from crimson Hat. IBM initially offered $185 a share on September 27, however red Hat's board of directors determined it changed into "inadequate," in line with the proxy.

purple Hat's board too requested its advisers to compose an inventory of other skills acquirers, who pink Hat courted unless affecting forward on the IBM deal on October 21. On October 28, the deal turned into introduced.

examine greater: They spoke with 7 insiders about IBM's $34 billion crimson Hat takeover — here's how it got here together

everybody else declined to bid

Microsoft, which, based on one source, is referenced outright through the proxy statement as "party A," first expressed interest in red Hat lower back in March. but Microsoft dropped out of the working on October 10, in keeping with the proxy, "citing issues about securing regulatory approvals of a strategic transaction within the US and Europe."

Microsoft declined to comment.

Google, which one supply celebrated turned into "birthday celebration B," met with purple Hat in the spring of 2018 to dispute partnerships. As a prefer permeate of IBM bought closer, Google continued to circulate forward with the sale process, but stopped brief of making an offer.

Google Cloud CEO Diane Greene, who is stepping down from the region in January 2019, spent months looking at pink Hat. Google

even though Google's former Cloud CEO Diane Greene spent lots of time with red Hat forward of its sale, she struggled to salvage lead from the company on her tremendous mergers-and-acquisitions aspirations, in response to one source.

So on October 20, Google formally declined to publish a notion and as an alternative asked if purple Hat would discover a industrial partnership and a minority fairness funding from Google.

Google did not immediately revert a request for comment.

Amazon, which one supply said turned into "birthday party C," got involved round October 12, when red Hat's executives reached out to the trade to peer if they were interested in a deal, according to the proxy. but on October 20, Amazon instructed purple Hat that it wasn't in a position to compose a suggestion.

regardless of its participation within the method, one supply stated it was probably Amazon was buying time. The enterprise wasn't interested in purple Hat, the supply mentioned, so a conducive deal as it was in staying on exact of what its cloud opponents at Microsoft and Google had been as much as.

Amazon didn't instantly revert a request for remark.


000-080 System x Sales Fundamentals V7

Study lead Prepared by Killexams.com IBM Dumps Experts


Killexams.com 000-080 Dumps and real Questions

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000-080 exam Dumps Source : System x Sales Fundamentals V7

Test Code : 000-080
Test cognomen : System x Sales Fundamentals V7
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Is Bitcoin's expense An Independent Variable? | killexams.com real questions and Pass4sure dumps

Introduction

One of the best techniques I know for sniffing out relationships among data sets is to simply upshot it on a scatter plot. I talked about this in my recent article, Bitcoin, Metcalfe and Lindy (BTC-USD)(OTCQX:GBTC)(COIN).

If you gain done this, and there seems to live some kindly of an association (zero correlation would live represented by a 0, perfect positive associations occur at +1, perfect negative associations are represented as -1), you may want to inspect for an equation to define this relationship.

One easy artery to achieve this is to exercise linear regression. But this approach comes with limitations and restrictions of its own. For one, linear regression is hypothetical to live used on conventional data sets. This means that outright those trend lines you drew in surpass on a monthly sales charts were actually lofty crimes to academia.

However, I contend that using regression in this artery has its merits for a number of reasons.

  • Even if it does not yield the perfect solution, often times the output is far ahead of existing models and does salvage us closer to the truth.
  • Wildly different approaches to a problem can sometimes arrive at the identical (or a very similar) solution. This is another artery of motto "there's more than one artery to skin a cat."
  • An unorthodox manner can live validated by one that is orthodox. This is what we'll live doing today.
  • I hope I gain made it lucid to my readers that my models are a drudgery in progress. I judge the drudgery is promising, I exercise them myself to compose decisions. But, I'm constantly chipping away at this bewilder they summon Bitcoin, constantly learning modern things and refining my approach. So, as I've said before, compose confident to prefer in information from multiple lofty quality sources and view what makes sense to you.

    Fortunately, I judge what you will view today lends further credibility to my pricing models, which were a completely modern approach that I pioneered.

    My drudgery so far

    Since I started posting on Seeking Alpha, I gain introduced many Bitcoin pricing models. I too gain published how the data were obtained, how to replicate my results, and from time to time I gain made enhancements to existing processes. If you would enjoy to review this work, you can achieve so below.

    Today we're going to prefer a step back and add another layer of validation to the belief that Bitcoin's expense should not live viewed in isolation. I contend that Bitcoin's expense is intimately related to the underlying network fundamentals. Let's recap:

  • Bitcoin is a currency that's too a network. Much enjoy other companionable networks, the value is in the community.
  • With no community, the expense is low. With a great and vigorous community, the expense is high.
  • The total number of transactions is one artery to quantify the age of Bitcoin. If it stops getting "older," it's dead. If it keeps growing, then the experiment continues.
  • We can proxy the number of users using unique addresses. This is not perfect but it is powerful.
  • We can proxy activity using the number of daily transactions.
  • Miner's hash power is related to the price, but too impacts confidence in the network's security and the businesses that invest hundreds of millions of dollars to control even 1% of the network hash rate.
  • Non-pear-a-what-now?

    Nonparametric statistics is a collection of statistical approaches and models that can live applied to some data to verify or disprove a hypothesis. According to Investopedia:

    Nonparametric statistics refer to a statistical manner in which the data is not required to lucky a conventional distribution. Nonparametric statistics uses data that is often ordinal, sense it does not rely on numbers, but rather a ranking or order of sorts. For example, a survey conveying consumer preferences ranging from enjoy to dislike would live considered ordinal data. - Investopedia.com

    Since the Bitcoin expense is typically the matter of my studies, and that expense changes with the passage of time, it's considered time series data, which is not normally distributed.

    So, today we're going to inspect at some ranking data and apply an approach called Spearman's Rho to view if the underlying assumptions that they gain made can live verified.

    By this I mean is Bitcoin's expense independent of the hash rate, the total transactions, the unique addresses and the daily transactions? Let's speak that their null hypothesis is this:

    H0: There is no relationship between the expense of Bitcoin and the hash rate, the number of daily transactions, the total number of transactions, and the number of unique addresses in use.

    H1: There is a relationship between the Bitcoin expense and the data I described above (hash rate, transactions, etc).

    We must either disprove the null hypothesis, or they must accept it. In this case, disproving the null hypothesis means they accept H1; that there is a relationship of some kind. Let's salvage started.

    Rankings

    The first thing they necessity to achieve is to prefer their data and apply ranks to the values which surpass can achieve very quickly.

    The artery the rankings drudgery is that the highest value will salvage the rank of "1," and each other value that's lower gets a number assigned to it that relates to its position in the stack. So, if they had 1533 data points (which they do) the lowest Bitcoin expense would give a rank of "1533." We're starting with the price, so:

  • Low expense (e.g. $0.06) = lofty Rank (1533)
  • High expense (e.g. $20k) = Low Rank (1)
  • We achieve the identical thing for each of their other data sets and they conclude up with something that looks enjoy this spreadsheet below.

    bitcoin ranking sheet Source: blockchain.com and author's spreadsheet

    Now that we've done outright that difficult work, let's achieve a visual check and view if these rankings attend to swagger together before they achieve any more math.

    bitcoin ranking chart Source: blockchain.com and author's charts

    What you're looking at is simply the rankings of each category on a line chart. The Y-axis is the ranking and the X-axis is time. As they can see, the rankings achieve attend to subside over time, indicating that the majority of lower values occurred in the past (the higher numeric rankings) and the higher values attend to live more recent.

    This visualization does appear to contradict their null hypothesis. In order to corroborate that their eyes are not deceiving us, let's Run that Spearman's Rho and view what it comes back with.

    To achieve this, they simply resolve for a correlation coefficient over the ranking data from each set. This was the result.

    Data Pair Correlation Coefficient P-value Price : Hash Rate 0.938386361 0 Price : Daily Transactions 0.885603855 0 Price : Unique Addresses 0.917587142 0 Price : Total Transactions 0.935037999 0

    Source: Author's spreadsheet (data from blockchain.com)

    The results bespeak that indeed there's a relationship between the rankings of these data sets. The direction of association is positive for outright groups and each P-value is well below the threshold for statistical significance.

    Therefore, they must reject the null hypothesis.

    What does it outright mean?

    It means that Bitcoin's expense is not an independent and unknowable phenomenon. Bitcoin's expense is just one portion of the Bitcoin ecosystem, and it happens to live one that's highly volatile. They can exercise this to their edge if they know the nature of the beast. Fortunately for us, outright the data is out in the open, if they know what to compose of it.

    Investing in Bitcoin may live a risky game, but if you arm yourself with the scholarship of how the system works, how it grows, and you know what failure looks like, then you'll live far ahead of the curve. By the way, if you're following anyone in the crypto space and they can't define failure or admit that it's possible, you are following the wrong person.

    Cheers,

    Hans

    This article was published first in Crypto Blue Chips.

    Disclosure: I am/we are long BTC-USD. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I gain no trade relationship with any company whose stock is mentioned in this article.


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    Amgen And Molecular Partners proclaim Strategic Collaboration In Immuno-Oncology | killexams.com real questions and Pass4sure dumps

    THOUSAND OAKS, Calif. and ZURICH-SCHLIEREN, Switzerland, Dec. 18, 2018 /PRNewswire/ -- Amgen AMGN, -0.86% and Molecular Partners AG (six:MOLN), a clinical-stage biotech company pioneering the exercise of DARPin [®] therapeutics, today announced a collaboration and license agreement for the clinical evolution and commercialization of MP0310 (FAP x 4-1BB). MP0310 is a preclinical molecule designed to locally activate immune cells in the tumor by binding to FAP on tumor stromal cells (localizer) and co-stimulating T cells via 4-1BB (immune modulator).

    Under the terms of the agreement, Amgen obtains exclusive global evolution and commercial rights for MP0310. The parties will jointly evaluate MP0310 in combination with Amgen`s oncology pipeline products, including its investigational gnaw [®] (bispecific T cell engager) molecules. Under the collaboration, Molecular Partners retains inescapable rights to develop and commercialize its proprietary DARPin [®] pipeline products in combination with MP0310.

    Molecular Partners will receive an upfront payment of $50 million and is eligible to receive up to $497 million in development, regulatory and commercial milestone payments, as well as double-digit, tiered royalties up to the lofty teens. The parties will share the clinical evolution costs in defined percentages for the first three indications matter to inescapable conditions. For outright additional clinical trials, Amgen is liable for outright evolution costs.

    "MP0310 is the first candidate out of their portfolio of localized and multi-specific immune-cell agonists. This collaboration with Amgen will allow us to test multiple combinations of MP0310 with other agents, leveraging the potential of MP0310. They anticipate MP0310 to enter the clinic in 2019," said Dr. Patrick Amstutz, chief executive officer of Molecular Partners. "The partnership with Amgen underlines the potential of MP0310 and the DARPin [®] platform to deliver novel therapeutic designs."

    "The sphere of immuno-oncology continues to rapidly evolve, and it's their belief that combination treatments will gain a major role to play in the future of cancer care," said David M. Reese, M.D., executive vice president of Research and evolution at Amgen. "We inspect forward to collaborating with Molecular Partners to combine MP0310 with inescapable oncology assets, including gnaw [®] molecules, to deliver improved outcomes for patients." 

    Conference summon and audio webcast  Molecular Partners will host a conference summon and audio webcast on Dec. 19, 2018, at 2 p.m. CET (1 p.m. GMT, 5 a.m. PT).

    In order to register for the conference call, please dial the following numbers approximately 10 minutes before the start of the presentation:

    Switzerland / Europe

    +41 (0) 58 310 5000

    UK

    +44 (0) 207 107 0613

    USA

    +1 (1) 631 570 5613

    Interested parties can access a corresponding audio webcast of the presentation. The webcast will live accessible, both live and as a replay, on the investors section of the company's website, along with the accompanying presentation slides.

    About DARPin® TherapeuticsDARPin [®] therapeutics are a modern class of protein therapeutics opening an extra dimension of multi-specificity and multi-functionality. DARPin [®] candidates hold multiple designed ankyrin reiterate binding domains and can engage more than five targets, offering potential benefits over conventional monoclonal antibodies or other currently available protein therapeutics. The DARPin [®] technology is a lickety-split and cost-effective drug discovery engine, producing drug candidates with ideal properties for evolution and lofty production yields. DARPin [®] is a registered trademark owned by Molecular Partners AG.

    About Molecular Partners AG Molecular Partners AG is a clinical-stage biopharmaceutical company that is developing a modern class of therapies known as DARPin [®] therapeutics. With a management team that includes many of the founding scientists, the company continues to attract talented individuals who share the fervor to develop breakthrough medicines for serious diseases. Molecular Partners has compounds in various stages of clinical and preclinical evolution and several more in the research stage, with a current focus on oncology and immuno-oncology. The company establishes research and evolution partnerships with leading pharmaceutical companies and is backed by established biotech investors.

    For more information regarding Molecular Partners AG, recede to: www.molecularpartners.com.

    About gnaw [®]  TechnologyBispecific T cell engager (BiTE [®] ) antibody construct is an innovative technology that can live engineered to target any tumor antigen expressed by any sort of cancer. The protein molecules are designed to abolish malignant cells using the patient's own immune system by bridging T cells to tumor cells. gnaw [®]  antibody construct helps connect the T cells to the targeted cell, with the intent of causing T cells to inject toxins which trigger cancer cell death (apoptosis). Amgen is developing gnaw [® ] antibody constructs to uniquely (or specifically) target numerous hematologic malignancies and solid tumors.

    About Amgen's Commitment to OncologyAmgen is committed to helping patients prefer on some of the toughest cancers, such as those that gain been resistant to drugs, those that progress rapidly through the corpse and those where limited treatment options exist. Amgen's supportive permeate treatments assist patients combat inescapable side effects of sturdy chemotherapy, and their targeted medicines and immunotherapies focus on more than a dozen different malignancies, ranging from blood cancers to solid tumors. With decades of tang providing therapies for cancer patients, Amgen continues to grow its portfolio of innovative and biosimilar oncology medicines.

    For more information, ensue us on www.twitter.com/amgenoncology.

    About Amgen Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools enjoy advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

    Amgen focuses on areas of lofty unmet medical necessity and leverages its expertise to strive for solutions that help health outcomes and dramatically help people's lives. A biotechnology pioneer since 1980, Amgen has grown to live one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

    For more information, visit www.amgen.com and ensue us on www.twitter.com/amgen.

    Amgen Forward-Looking StatementsThis advice release contains forward-looking statements that are based on the current expectations and beliefs of Amgen. outright statements, other than statements of historical fact, are statements that could live deemed forward-looking statements, including estimates of revenues, operating margins, capital expenditures, cash, other pecuniary metrics, expected legal, arbitration, political, regulatory or clinical results or practices, customer and prescriber patterns or practices, reimbursement activities and outcomes and other such estimates and results. Forward-looking statements involve significant risks and uncertainties, including those discussed below and more fully described in the Securities and Exchange Commission reports filed by Amgen, including its most recent annual report on shape 10-K and any subsequent sporadic reports on shape 10-Q and current reports on shape 8-K. Unless otherwise noted, Amgen is providing this information as of the date of this advice release and does not undertake any duty to update any forward-looking statements contained in this document as a result of modern information, future events or otherwise. No forward-looking statement can live guaranteed, and actual results may disagree materially from those Amgen project. Amgen's results may live affected by its ability to successfully market both modern and existing products domestically and internationally, clinical and regulatory developments involving current and future products, sales growth of recently launched products, competition from other products including biosimilars, difficulties or delays in manufacturing its products and global economic conditions. In addition, sales of Amgen's products are affected by pricing pressure, political and public scrutiny and reimbursement policies imposed by third-party payers, including governments, private insurance plans and managed permeate providers and may live affected by regulatory, clinical and guideline developments and domestic and international trends toward managed permeate and healthcare cost containment. Furthermore, Amgen's research, testing, pricing, marketing and other operations are matter to extensive regulation by domestic and foreign government regulatory authorities. Amgen or others could identify safety, side effects or manufacturing problems with its products, including its devices, after they are on the market. Amgen's trade may live impacted by government investigations, litigation and product liability claims. In addition, Amgen's trade may live impacted by the adoption of modern tax legislation or exposure to additional tax liabilities. While Amgen routinely obtains patents for its products and technology, the protection offered by its patents and patent applications may live challenged, invalidated or circumvented by its competitors, or Amgen may fail to prevail in present and future intellectual property litigation. Amgen performs a substantial amount of its commercial manufacturing activities at a few key facilities, including in Puerto Rico, and too depends on third parties for a portion of its manufacturing activities, and limits on supply may constrain sales of inescapable of its current products and product candidate development. In addition, Amgen competes with other companies with respect to many of its marketed products as well as for the discovery and evolution of modern products. Discovery or identification of modern product candidates or evolution of modern indications for existing products cannot live guaranteed and movement from concept to product is uncertain; consequently, there can live no guarantee that any particular product candidate or evolution of a modern indication for an existing product will live successful and become a commercial product. Further, some raw materials, medical devices and component parts for Amgen's products are supplied by sole third-party suppliers. inescapable of Amgen's distributors, customers and payers gain substantial purchasing leverage in their dealings with Amgen. The discovery of significant problems with a product similar to one of Amgen's products that implicate an entire class of products could gain a material adverse upshot on sales of the affected products and on its trade and results of operations. Amgen's efforts to acquire other companies or products and to integrate the operations of companies Amgen has acquired may not live successful. A breakdown, cyberattack or information security breach could compromise the confidentiality, integrity and availability of Amgen's systems and Amgen's data. Amgen's stock expense may live volatile and may live affected by a number of events. Amgen's trade performance could influence or circumscribe the ability of the Amgen Board of Directors to declare a dividend or its ability to pay a dividend or repurchase its common stock. Amgen may not live able to access the capital and credit markets on terms that are conducive to it, or at all.

    The scientific information discussed in this advice release related to Amgen's product candidates is preliminary and investigative. Such product candidates are not approved by the U.S. Food and Drug Administration, and no conclusions can or should live drawn regarding the safety or effectiveness of the product candidates.

    Molecular Partners Forward-Looking StatementsThis communication does not constitute an offer or invitation to subscribe for or purchase any securities of Molecular Partners AG. This publication may hold inescapable forward-looking statements and assessments or intentions concerning the company and its business. Such statements involve inescapable risks, uncertainties and other factors which could occasions the actual results, pecuniary condition, performance or achievements of the company to live materially different from those expressed or implied by such statements. Readers should therefore not region reliance on these statements, particularly not in connection with any contract or investment decision. The company disclaims any duty to update these forward-looking statements, assessments or intentions.

    CONTACT: Amgen, Thousand OaksKristen Davis, 805-447-3008(media)Trish Hawkins, 805-447-5631 (media)Arvind Sood, 805-447-1060 (investors)

    CONTACT: Molecular Partners, Zurich-Schlieren, SwitzerlandPatrick Amstutz, CEO, +41 44 755 77 00Thomas Schneckenburger, +41 44 755 5728 (IR Europe)Susan A. Noonan, +1 212 966 3650 (IR USA)Lisa Raffensperger, +1 617 903 8783 (international media)

    View original content to download multimedia:http://www.prnewswire.com/news-releases/amgen-and-molecular-partners-announce-strategic-collaboration-in-immuno-oncology-300768619.html

    SOURCE Amgen

    Copyright (C) 2018 PR Newswire. outright rights reserved



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